Results 51 to 60 of about 419,255 (408)
Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo
Science, 2018 Mapping the vertebrate developmental landscape As embryos develop, numerous cell types with distinct functions and morphologies arise from pluripotent cells.
Daniel E. Wagner +5 more
semanticscholar +1 more source
Characterization of Hspb8 in Zebrafish [PDF]
Cells, 2020 Hspb8 is a member of the small heat shock protein (sHSP) family. Its expression is known to be upregulated under heat shock. This protein interacts with different partners and can, therefore, be involved in various processes relevant to tissue integrity and functioning.
Marta Migocka-Patrzałek +5 more
openaire +3 more sources
New zebrafish models of neurodegeneration [PDF]
, 2015 In modern biomedicine, the increasing need to develop experimental models to further our understanding of disease conditions and delineate innovative treatments has found in the zebrafish (Danio rerio) an experimental model, and indeed a valuable asset ...
A Nasevicius +28 more
core +1 more source
Current Opinion in Genetics & Development, 1998 Signals from the organizer play a crucial role in patterning the vertebrate embryo. Recent molecular analysis of zebrafish mutations has established an essential role for BMP2 and chordin in organizer function and has identified one-eyed pinhead as a novel EGF-like gene involved in prechordal plate and endoderm formation.
Alexander F. Schier, William S. Talbot
openaire +3 more sources
Lecithin-Based Dermal Drug Delivery for Anti-Pigmentation Maize Ceramide
Molecules, 2020 Ceramides have several well-known biological properties, including anti-pigmentation and anti-melanogenesis, which make them applicable for use in skincare products in cosmetics. However, the efficacy of ceramides is still limited.
Kazuhiro Kagotani +7 more
doaj +1 more source
Decreasing nuclear volume concentrates DNA and enforces transcription factor-chromatin associations during Zebrafish genome activation [PDF]
Nature Communications, 9(1), 5218 (2018), 2017 Zygotic genome activation (ZGA), the onset of transcription after initial quiescence, is a major developmental step in many species, which occurs after ten cell divisions in Zebrafish embryos. How transcription factor-chromatin interactions evolve during early development to support ZGA is largely unknown.
arxiv +1 more source
Methods, 2015 From a hitherto underappreciated phenomenon, autophagy has become one of the most intensively studied cellular processes in recent years. Its role in cellular homeostasis, development and disease is supported by a fast growing body of evidence. Surprisingly, only a small fraction of new observations regarding the physiological functions of cellular ...
Máté Varga, Erika Fodor, Tibor Vellai
openaire +2 more sources
Zebrafish as a Successful Animal Model for Screening Toxicity of Medicinal Plants
Plants, 2020 The zebrafish (Danio rerio) is used as an embryonic and larval model to perform in vitro experiments and developmental toxicity studies. Zebrafish may be used to determine the toxicity of samples in early screening assays, often in a high-throughput ...
A. M. Chahardehi +2 more
semanticscholar +1 more source
Zebrafish Larvae as a Behavioral Model in Neuropharmacology
Biomedicines, 2019 Zebrafish larvae show a clear and distinct pattern of swimming in response to light and dark conditions, following the development of a swim bladder at 4 days post fertilization.
R. Basnet +4 more
semanticscholar +1 more source
Studying Autophagy in Zebrafish [PDF]
Cells, 2017 Autophagy is an evolutionarily conserved catabolic process which allows lysosomal degradation of complex cytoplasmic components into basic biomolecules that are recycled for further cellular use. Autophagy is critical for cellular homeostasis and for degradation of misfolded proteins and damaged organelles as well as intracellular pathogens.
Mathai Benan, J. +2 more
openaire +7 more sources