Results 51 to 60 of about 373,753 (331)

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Natterin bridges IFN-φ1 and non-canonical inflammasome pathways via CRFB1/Gbp4 to license Caspy2-mediated antibacterial immunity

Frontiers in Cellular and Infection Microbiology
The Natterin protein family represents an evolutionarily conserved group of immune effectors in teleosts, yet its broader regulatory role in host defense remains poorly understood.
Darlan Gusso, Felipe Justiniano Pinto, Aline Ingrid Andrade-Barros, Jefferson Thiago Gonçalves Bernardo, Carlos DeOcesano-Pereira, Monica Lopes-Ferreira, Carla Lima   +6 more
doaj   +1 more source

Temporal Variations of CAT, GSH, and LPO in Gills and Livers of Zebrafish, Danio Rerio, Exposed to Dimethoate

Archives of Polish Fisheries, 2014
Pesticides are designed to kill a very wide range of undesirable organisms, but they simultaneously adversely affect non-target organisms in ecosystems.
Ansari Shabnam, Ansari Badre Alam
doaj   +1 more source

Conserved and Divergent Features of Adult Neurogenesis in Zebrafish

Frontiers in Cell and Developmental Biology, 2020
Adult neurogenesis, i.e., the generation of neurons from neural stem cells (NSCs) in the adult brain, contributes to brain plasticity in all vertebrates.
Miriam Labusch, Miriam Labusch, Laure Mancini, Laure Mancini, David Morizet, David Morizet, Laure Bally-Cuif   +6 more
doaj   +1 more source

BATCH-GE : batch analysis of next-generation sequencing data for genome editing assessment [PDF]

, 2016
Targeted mutagenesis by the CRISPR/Cas9 system is currently revolutionizing genetics. The ease of this technique has enabled genome engineering in-vitro and in a range of model organisms and has pushed experimental dimensions to unprecedented proportions.
Boel, Annekatrien, Callewaert, Bert, Coucke, Paul, De Paepe, Anne, De Rocker, Nina, Menten, Björn, Steyaert, Wouter, Willaert, Andy   +7 more
core   +2 more sources

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

Advanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo, Ewa Anna Oprzeska‐Zingrebe, Mariana Kozlowska, Lennart Hilbert, Iliya D. Stoev   +4 more
wiley   +1 more source

Zebrafish as an Integrative Model for Central Nervous System Research: Current Advances and Translational Perspectives

Life
Central nervous system disorders represent a heterogeneous set of conditions triggered by genetic alterations, environmental exposures, infections, injuries, and even iatrogenic causes.
Lidia Pansera, Kamel Mhalhel, Mauro Cavallaro, Marialuisa Aragona, Rosaria Laurà, Maria Levanti, Maria Cristina Guerrera, Francesco Abbate, Antonino Germanà, Giuseppe Montalbano   +9 more
doaj   +1 more source

Role of Extracellular Mycobacteria in Blood-Retinal Barrier Invasion in a Zebrafish Model of Ocular TB

Pathogens, 2021
Intraocular inflammation following mycobacterial dissemination to the eye is common in tuberculosis (TB)-endemic countries. However, the early host–pathogen interactions during ocular dissemination are unknown.
Santhosh Kumar Damera, Ranjan Kumar Panigrahi, Sanchita Mitra, Soumyava Basu   +3 more
doaj   +1 more source

Changes in zebrafish (Danio rerio) lens crystallin content during development. [PDF]

, 2013
PurposeThe roles that crystallin proteins play during lens development are not well understood. Similarities in the adult crystallin composition of mammalian and zebrafish lenses have made the latter a valuable model for examining lens function.
Corbin, Rebecca W, Ding, Linlin, Horwitz, Joseph, Posner, Mason, Wages, Phillip   +4 more
core   +1 more source

Spin‐Dependent Generation of Surface‐Bound Radicals Toward Selective and Long‐Lasting Water Purification

Advanced Functional Materials, EarlyView.
This study develops a novel atomic engineering strategy to fine‐tune the spin state of α‐Fe2O3 catalysts toward a medium‐spin state, thereby modulating peroxymonosulfate activation and selectively yielding surface‐bound radicals. Compared with free radicals, surface‐bound radicals exhibit moderated oxidation potential, extended lifespan, surface ...
Shuyu Wang, Zhonglin Chen, Jimin Shen, Pengwei Yan, Jing Kang, Binyuan Wang, Shengxin Zhao, Xiaoguang Duan   +7 more
wiley   +1 more source