Results 81 to 90 of about 419,255 (408)

Negative cell cycle regulation by calcineurin is necessary for proper beta cell regeneration in zebrafish

open access: yeseLife
Stimulation of pancreatic beta cell regeneration could be a therapeutic lead to treat diabetes. Unlike humans, the zebrafish can efficiently regenerate beta cells, notably from ductal pancreatic progenitors.
Laura Massoz   +9 more
doaj   +1 more source

Deep learning-based framework for cardiac function assessment in embryonic zebrafish from heart beating videos [PDF]

open access: yesarXiv, 2021
Zebrafish is a powerful and widely-used model system for a host of biological investigations including cardiovascular studies and genetic screening. Zebrafish are readily assessable during developmental stages; however, the current methods for quantification and monitoring of cardiac functions mostly involve tedious manual work and inconsistent ...
arxiv  

Zebrafish as animal model for aquaculture nutrition research. [PDF]

open access: yes, 2014
The aquaculture industry continues to promote the diversification of ingredients used in aquafeed in order to achieve a more sustainable aquaculture production system. The evaluation of large numbers of diets in aquaculture species is costly and requires
Feijoo, Carmen G   +2 more
core   +2 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Zebrafish: A Model Deciphering the Impact of Flavonoids on Neurodegenerative Disorders

open access: yesCells, 2023
Over the past century, advances in biotechnology, biochemistry, and pharmacognosy have spotlighted flavonoids, polyphenolic secondary metabolites that have the ability to modulate many pathways involved in various biological mechanisms, including those ...
Kamel Mhalhel   +8 more
doaj   +1 more source

3D-ZeF: A 3D Zebrafish Tracking Benchmark Dataset [PDF]

open access: yesarXiv, 2020
In this work we present a novel publicly available stereo based 3D RGB dataset for multi-object zebrafish tracking, called 3D-ZeF. Zebrafish is an increasingly popular model organism used for studying neurological disorders, drug addiction, and more. Behavioral analysis is often a critical part of such research.
arxiv  

Calsequestrins in skeletal and cardiac muscle from adult Danio rerio [PDF]

open access: yes, 2015
Calsequestrin (Casq) is a high capacity, low affinity Ca2+-binding protein, critical for Ca2+-buffering in cardiac and skeletal muscle sarcoplasmic reticulum. All vertebrates have multiple genes encoding for different Casq isoforms.
Argenton, Francesco   +6 more
core   +1 more source

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

open access: yesFEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston   +7 more
wiley   +1 more source

Maintenance of Zebrafish Lines at the European Zebrafish Resource Center [PDF]

open access: yesZebrafish, 2016
We have established a European Zebrafish Resource Center (EZRC) at the KIT. This center not only maintains and distributes a large number of existing mutant and transgenic zebrafish lines but also gives zebrafish researchers access to screening services and technologies such as imaging and high-throughput sequencing, provided by the Institute of ...
Geisler, Robert   +4 more
openaire   +4 more sources

Zebrafish models of sarcopenia [PDF]

open access: yesDisease Models & Mechanisms, 2020
Sarcopenia - the accelerated age-related loss of muscle mass and function - is an under-diagnosed condition, and is central to deteriorating mobility, disability and frailty in older age. There is a lack of treatment options for older adults at risk of sarcopenia.
Alon Daya   +2 more
openaire   +4 more sources

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