Results 81 to 90 of about 367,304 (292)

Atlas of Cellular Dynamics during Zebrafish Adult Kidney Regeneration

Stem Cells International, 2015
The zebrafish is a useful animal model to study the signaling pathways that orchestrate kidney regeneration, as its renal nephrons are simple, yet they maintain the biological complexity inherent to that of higher vertebrate organisms including mammals ...
Kristen K. McCampbell, Kristin N. Springer, Rebecca A. Wingert   +2 more
doaj   +1 more source

Photothermally Powered 3D Microgels Mechanically Regulate Mesenchymal Stem Cells Under Anisotropic Force

Advanced Materials, EarlyView.
The photothermally powered microgel is designed to mechanically train mesenchymal stem cells using spatially patterned exogenous forces in three‐dimensional (3D) workspaces. When microgels are activated selectively via photothermal actuation, locally confined tens of nN forces are exerted on cells, triggering osteogenic differentiation in encapsulated ...
Chen Wang, Nergishan İyisan, Philipp Harder, Valentin H. K. Fell, Viktorija Kozina, Hendrik Dietz, Olivia M. Merkel, Berna Özkale   +7 more
wiley   +1 more source

Trehalose Treatment in Zebrafish Model of Lafora Disease [PDF]

, 2022
Stefania Della Vecchia, Asahi Ogi, Rosario Licitra, Francesca Abramo, Gabriele Nardi, Serena Mero, Silvia Landi, Roberta Battini, Federico Sicca, Gian Michele Ratto, Filippo M. Santorelli, Maria Marchese   +11 more
openalex   +1 more source

The First Review on Nano‐Agricultural Applications of MXene and MBene‐Based Materials for Plant‐Immunoengineering, Controlled Protection, and Inducing Biostimulation Mechanisms

Advanced Materials, EarlyView.
MXene and MBene nanomaterials show significant potential in addressing critical challenges in biomedicine, applied biology, agriculture, and the environment. From a nano‐agricultural perspective, this relatively young field has witnessed emerging advances towards applications for plant‐immunoengineering, biostimulation, and controlled delivery ...
Alireza Rafieerad, Ahmad Amiri, Maik Böhmer, Soofia Khanahmadi   +3 more
wiley   +1 more source

Methanol and isopropanol embryo dosage response curves for wild-type and ethanol-sensitive zebrafish [PDF]

, 2016
It is well established that ethanol has an array of negative effects on developing embryos, from craniofacial abnormalities to cognitive deficits and behavioral disorders.
Anderson, Ashley
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

αKlotho Regulates Age-Associated Vascular Calcification and Lifespan in Zebrafish

Cell Reports, 2019
Summary: The hormone αKlotho regulates lifespan in mice, as knockouts die early of what appears to be accelerated aging due to hyperphosphatemia and soft tissue calcification. In contrast, the overexpression of αKlotho increases lifespan.
Ajeet Pratap Singh, Maria X. Sosa, Jian Fang, Shiva Kumar Shanmukhappa, Alexis Hubaud, Caroline H. Fawcett, Gregory J. Molind, Tingwei Tsai, Paola Capodieci, Kristie Wetzel, Ellen Sanchez, Guangliang Wang, Matthew Coble, Wenlong Tang, Samuel M. Cadena, Mark C. Fishman, David J. Glass   +16 more
doaj   +1 more source

Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system. [PDF]

, 2017
Precise genetic modifications in model animals are essential for biomedical research. Here, we report a programmable "base editing" system to induce precise base conversion with high efficiency in zebrafish. Using cytidine deaminase fused to Cas9 nickase,
Bai, Haipeng, Huang, Haigen, Li, Song, Lin, Shuo, Lu, Xiaochan, Qin, Wei, Xu, Jason, Zhang, Yihan   +7 more
core   +1 more source

Macrophages Mediate Mesoscale Brain Mechanical Homeostasis

Advanced Materials, EarlyView.
We investigated the role of infiltrating immune cells in sculpting the developing brain. Using Brillouin microscopy and active microrheology, we found microglia actively maintain tissue viscoelasticity. Moreover, colony stimulating factor one receptor (CSF1R)‐driven stromal remodeling alters brain mechanics in vivo. These findings link immune activity,
Woong Young So, Bailey Johnson, Patricia B. Gordon, Kevin S. Bishop, Hyeyeon Gong, Hannah A Burr, Jack Rory Staunton, Chenchen Handler, Khanh Loan Ly, Raman Sood, Giuliano Scarcelli, Kandice Tanner   +11 more
wiley   +1 more source

Angiopoietin 1 and integrin beta 1b are vital for zebrafish brain development

Frontiers in Cellular Neuroscience
IntroductionAngiopoietin 1 (angpt1) is essential for angiogenesis. However, its role in neurogenesis is largely undiscovered. This study aimed to identify the role of angpt1 in brain development, the mode of action of angpt1, and its prime targets in the
Yu-Chia Chen, Yu-Chia Chen, Tomás A. Martins, Tomás A. Martins, Valentina Marchica, Valentina Marchica, Pertti Panula, Pertti Panula   +7 more
doaj   +1 more source