Results 51 to 60 of about 103,876 (310)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Cleft analysis of Zika virus non-structural protein 1
Asian Pacific Journal of Tropical Biomedicine, 2017 The non-structural protein 1 is an important molecule of the viruses in flavivirus group including to Zika virus. Recently, the NS1 of Zika virus was discovered.
Somsri Wiwanitkit, Viroj Wiwanitkit
doaj +1 more source
Zika virus infection reprograms global transcription of host cells to allow sustained infection. [PDF]
, 2017 Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and Guillain-Barré syndrome. There are currently no targeted therapies for ZIKV infection.
Bansal, Vikas +5 more
core +2 more sources
Characterization of Zika virus endocytic pathways in human glioblastoma cells [PDF]
, 2020 Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Du, T +11 more
core +1 more source
FEBS Open Bio, EarlyView.Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
Projecting Month of Birth for At-Risk Infants after Zika Virus Disease Outbreaks
Emerging Infectious Diseases, 2016 The marked increase in infants born with microcephaly in Brazil after a 2015 outbreak of Zika virus (Zika virus) disease suggests an association between maternal Zika virus infection and congenital microcephaly.
Jennita Reefhuis +9 more
doaj +1 more source
Zika: what we do and do not know based on the experiences of Brazil [PDF]
Epidemiology and Health, 2016 OBJECTIVES: Zika virus, which was first discovered in 1947, has become a global threat to human health as it is rapidly spreading through Latin America, the Caribbean, the US and Asia, after causing a large outbreak in the Northeast region of Brazil in ...
Cristina Possas
doaj +1 more source
The Zika Virus Threat: How Concerns About Scientists May Undermine Efforts to Combat the Pandemic [PDF]
, 2017 Using data from the University of New Hampshire’s October 2016 Granite State Poll, authors Thomas Safford, Lawrence Hamilton, and Emily Whitmore investigate how New Hampshire residents view the Zika crisis.
Hamilton, Lawrence C. +2 more
core +2 more sources
Specific detection of dengue and Zika virus antibodies using envelope proteins with mutations in the conserved fusion loop [PDF]
, 2017 Detection of antibodies is widely used for the diagnosis of infections with arthropod-borne flaviviruses including dengue (DENV) and Zika virus (ZIKV). Due to the emergence of ZIKV in areas endemic for DENV, massive co-circulation is observed and methods
Barzon, Luisa +12 more
core +2 more sources
Advanced Functional Materials, EarlyView.Epitaxial piezoelectric α‐quartz/Si BioNEMS sensors, made using soft chemistry, effectively detect the Chikungunya virus. They have a mass sensitivity of 205 pg Hz−1 in liquid and can detect the virus at a limit of 9 ng mL−1. This development enables high‐frequency mass devices for point‐of‐care testing in healthcare and other electronic applications ...
Raissa Rathar +12 more
wiley +1 more source