Results 61 to 70 of about 2,499,899 (220)

The Dual Role of the Immune Response in Reproductive Organs During Zika Virus Infection

Frontiers in Immunology, 2019
Zika virus is a mosquito-borne viral disease that emerged as a significant health problem in the Americas after an epidemic in 2015. Especially concerning are cases where Zika is linked to the development of brain abnormalities in newborns.
Haruki Arévalo Romero, Tania A. Vargas Pavía, Manuel A. Velázquez Cervantes, Arturo Flores Pliego, Addy C. Helguera Repetto, Moises León Juárez   +5 more
doaj   +1 more source

Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes

The FEBS Journal, EarlyView.
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli, Rupesh Balaji Jayachandran, Jack Whitehead, Cédric Leyrat, Annabel v. Clanner, Guido C Paesen, Max Renner   +6 more
wiley   +1 more source

The inoculum dose of Zika virus can affect the viral replication dynamics, cytokine responses and survival rate in immunocompromised AG129 mice

Molecular Biomedicine
Zika virus, a mosquito-borne arbovirus, has repeatedly caused large pandemics with symptoms worsening from mild and self-limiting diseases to Guillain–Barré syndrome in adults and fetal microcephaly in newborns.
Yuhuan Yan, Hao Yang, Yun Yang, Junbin Wang, Yanan Zhou, Cong Tang, Bai Li, Qing Huang, Ran An, Xiaoming Liang, Dongdong Lin, Wenhai Yu, Changfa Fan, Shuaiyao Lu   +13 more
doaj   +1 more source

Knowledge, attitudes, and practices of women of childbearing age testing negative for Zika virus in Kentucky, 2016

Preventive Medicine Reports, 2018
Because infection with Zika virus during pregnancy can cause microcephaly and other birth defects, women of childbearing age are an important population for targeting of Zika-related public health messaging.
Kristen Heitzinger, Douglas A. Thoroughman, Kimberly A. Porter   +2 more
doaj   +1 more source

Advances in Cytosolic dsRNA Sensing of Viral Infections

Immunology &Cell Biology, EarlyView.
Activation of cytosolic dsRNA sensors by viral infection generates multiple outcomes. dsRNA generated during viral infection, either of viral origin or from endogenous sources, can activate multiple cytosolic dsRNA sensors. Activation of PKR critically induces protein translation shutdown via phosphorylation of eukaryotic translation initiation factor ...
Sofia Maceratessi, Natalia G. Sampaio
wiley   +1 more source

Zika Virus–Associated Cognitive Impairment in Adolescent, 2016

Emerging Infectious Diseases, 2017
Incidence of neurologic manifestations associated with Zika virus infection has been increasing. In 2016, neuropsychological and cognitive changes developed in an adolescent after travel to a Zika virus–endemic area.
Jason Zucker, Natalie Neu, Claudia A. Chiriboga, Veronica J. Hinton, Marc Leonardo, Arif Sheikh, Kiran Thakur   +6 more
doaj   +1 more source

Preimaginal development of Aedes aegypti L. (Diptera: Culicidae) in brackish water gives rise to adult mosquitoes with thicker cuticles and greater insecticide resistance

Medical and Veterinary Entomology, EarlyView.
The principal arboviral vector Aedes aegypti can develop in coastal brackish water field habitats (0.5–15 g/L salt) with larvae possessing thicker cuticles and greater resistance to the larvicide Temephos. Females emerging from brackish water‐developing preimaginal stages are now shown to have thicker and remodelled leg and abdominal cuticles and ...
Kokila Sivabalakrishnan, Andrew Hemphill, S. H. P. Parakrama Karunaratne, Arunasalam Naguleswaran, Isabel Roditi, Sinnathamby N. Surendran, Ranjan Ramasamy   +6 more
wiley   +1 more source

Detailed Analyses of Zika Virus Tropism in Culex quinquefasciatus Reveal Systemic Refractoriness

mBio, 2020
The role of Culex quinquefasciatus in Zika virus transmission has been debated since the epidemic of Zika occurred in the Americas in 2015 to 2016. The majority of studies have found no evidence that C.
Hannah J. MacLeod, George Dimopoulos
doaj   +1 more source

Investigating the association between weather variables and Aedes albopictus abundance in Windsor, Ontario

Medical and Veterinary Entomology, EarlyView.
Trapping completed by Windsor‐Essex County Health Unit. Data analysis using trap and weather data. Canadian weather thresholds are associated with increased mosquito abundance. Abstract Aedes albopictus (Diptera: Culicidae) is notorious for transmitting several pathogens of public health importance.
Keana Shahin, Katie M. Clow, Olaf Berke, Ilaria Dorigatti, Victoria Ng   +4 more
wiley   +1 more source

Nervous System Injury and Neuroimaging of Zika Virus Infection

Frontiers in Neurology, 2018
In 2016, World Health Organization announced Zika virus infection and its neurological sequalae are a public health emergency of global scope. Preliminary studies have confirmed a relationship between Zika virus infection and certain neurological ...
Shanshan Wu, Shanshan Wu, Yu Zeng, Alexander Lerner, Bo Gao, Meng Law   +5 more
doaj   +1 more source