ZINC-22 - A Free Multi-Billion-Scale Database of Tangible Compounds for Ligand Discovery [PDF]
Purchasable chemical space has grown rapidly into the tens of billions of molecules providing unprecedented opportunities for ligand discovery, but also straining the tools that might exploit these molecules at scale. We have therefore developed ZINC-22,
John, Gutierrez +7 more
core +2 more sources
Health hazards resulting from exposure to zinc and its inorganic compounds in industry
This article deals with health risks resulting from exposure to zinc and its inorganic compounds in industry. The main source of zinc exposure are fumes generated during thermal and chemical processes, mainly zinc oxide fume formed by immediate oxidation
Daria Pakulska, Sławomir Czerczak
doaj +1 more source
Antiamoebic Properties of Ceftriaxone and Zinc-Oxide–Cyclodextrin-Conjugated Ceftriaxone
Acanthamoeba castellanii is a ubiquitous free-living amoeba capable of instigating keratitis and granulomatous amoebic encephalitis in humans. Treatment remains limited and inconsistent.
Zinb Makhlouf +6 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Determination of Oxygen in Zinc Compounds [PDF]
Abstract Oxygen in zinc compounds was determined by a modification of the method of Schütze. Oxygen in some zinc compounds such as zinc oxide, zinc acetate and zinc oxalate could not be determined by the usual method. The carrier gas method of adding carbon was employed for the determination of total oxygen.
Kazuo Imaeda, Takeo Kuriki, Keiko Ohsawa
openaire +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The present work elucidated the effect of the new zinc coordination compound, with the formula {[Zn3(HL)2(H2O)6](SO4)2⋅1.5dmf∙2.5H2O}n (CCZn) (H2L=2,6-diacetylpyridine bis(isonicotinoylhydrazone), on the growth and development processes of seedlings of ...
Lilia BRÎNZĂ +3 more
doaj +1 more source
EFFECT OF NANO ZINC OXIDE ON TENSILE PROPERTIES OF NATURAL RUBBER COMPOSITE
This study investigates the effect of Nano-zinc oxide on tensile properties of natural rubber composites by replacing the conventional zinc oxide by Nano-zinc oxide as an activator.
Saja Q. Mohammed +2 more
doaj +1 more source
Effect of supplementation with zinc and other micronutrients on malaria in Tanzanian children: a randomised trial. [PDF]
BACKGROUND: It is uncertain to what extent oral supplementation with zinc can reduce episodes of malaria in endemic areas. Protection may depend on other nutrients. We measured the effect of supplementation with zinc and other nutrients on malaria rates.
Veenemans, J. +96 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

