Systemic treatment for lung carcinoids: from bench to bedside
AbstractIn the huge spectrum of lung neuroendocrine neoplasms, typical and atypical carcinoids should be considered as a separate biological entity from poorly differentiated forms, harboring peculiar molecular alterations. Despite their indolent behavior, lung carcinoids correlate with a worse survival.
Mariangela Torniai +7 more
wiley +1 more source
Angiogenesis in metastatic colorectal cancer and the benefits of targeted therapy
The diverse pathways and molecules involved in angiogenesis, the formation of new blood vessels, have been targeted for the treatment of colorectal and other cancers.
Sun Weijing
doaj +1 more source
Background: Association of drugs acting against different antiangiogenic mechanisms may increase therapeutic effect and reduce resistance. Noninvasive monitoring of changes in the antiangiogenic response of individual tumors could guide selection and ...
Michele Lamuraglia MD, PhD +8 more
doaj +1 more source
Treatment Strategies in Colorectal Cancer [PDF]
Colorectal cancer is known to be one of the most commonly diagnosed cancers worldwide. It maintains a high mortality rate despite the newest methodological therapeutic approaches adopted in various academic establishments.
Daaboul, Hamid Elia, El-Sibai, Mirvat
core +1 more source
Integrative meta-analysis identifies microRNA-regulated networks in infantile hemangioma [PDF]
BACKGROUND: Hemangioma is a common benign tumor in the childhood; however our knowledge about the molecular mechanisms of hemangioma development and progression are still limited.
Fábio E. Severino +5 more
core +2 more sources
Efectividad a corto plazo de Ziv-Aflibercept intravítreo para el tratamiento del edema macular secundario a la oclusión de la vena retiniana [PDF]
Objective: To determine the short-term effectiveness of intravitreal Ziv-Aflibercept (IV-ZA) for the treatment of macular edema secondary to retinal vein occlusion (MESRVO).
García-Perdomo , Herney +6 more
core +2 more sources
Osteonecrosis of the Jaw Associated with Antiangiogenics in Antiresorptive-Naive Patient: A Comprehensive Review of the Literature [PDF]
Objectives. To review the available literature on medication-related osteonecrosis of the jaw (MRONJ) associated with antiangiogenics in antiresorptive-naïve individuals. Methods.
Fedele, S, Pimolbutr, K, Porter, S
core
Purpose The aim of this study was to evaluate the efficacy of intravitreal injection of Ziv-aflibercept before small-gauge pars plana vitrectomy compared to pars plana vitrectomy alone in eyes with advanced diabetic eye disease. Patients and methods
Amin E. Nawar, Ahmed R. Alagorie
doaj +1 more source
Three-month outcome of intravitreal ziv-aflibercept in eyes with diabetic macular oedema [PDF]
Purpose We report the 3-month efficacy of monthly intravitreal ziv-aflibercept in patients with diabetic macular oedema (DME). Methods Prospectively, consecutive patients with DME underwent intravitreal injection of 0.05 ml of compounded ziv-aflibercept (
Chhablani, Jay Kumar +2 more
core +1 more source
Managing Pharmacotherapy in People Living With HIV and Concomitant Malignancy. [PDF]
Objective: To describe data with selected malignancies in people living with HIV (PLWH) and HIV in individuals affected by both conditions and to summarize drug-drug interactions (DDIs) with clinical recommendations for point-of-care review of ...
Chan, Alexandre +3 more
core +1 more source

