Anti-VEGF agents in metastatic colorectal cancer (mCRC): are they all alike?
Cancer Management and Research, 2013 Muhammad Wasif Saif GI Oncology Program, Tufts University School of Medicine, Boston, MA, USA Abstract: Bevacizumab is a monoclonal antibody that binds and neutralizes vascular endothelial growth factor (VEGF)-A, a key player in the angiogenesis pathway.
Saif MW
doaj
Southwest Oncology Group S0802: A Randomized, Phase II Trial of Weekly Topotecan With and Without Ziv-Aflibercept in Patients With Platinum-Treated Small-Cell Lung Cancer [PDF]
, 2014 Jeffrey W. Allen +9 more
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Progression of Ziv-aflibercept on metastatic colorectal cancer [PDF]
, 2015 针对特异性分子靶点的靶向药物治疗已成为转移性结直肠癌(M CrC)治疗的新方向。2012年zIV-阿柏西普被美国食品和药物管理局批准用于M CrC患者,zIV-阿柏西普是一种作用于血管生成信号通路的重组融合蛋白,通过与血管内皮生长因子(VEgf)受体结合,从而阻断肿瘤的生长和转移。一项Ⅲ期临床研究结果显示zIV-阿柏西普能显著延长M CrC患者的生存期。本文结合国内外最新研究报道,对zIV-阿柏西普治疗M CrC的研究进展作一综述。Targeted drug therapy for specific ...
宋敏
core
Three-Month Outcome of Ziv-Aflibercept for Diabetic Macular Edema
Advances in Ophthalmology & Visual System, 2016 1.1.Purpose:Is to show the 3-month efficacy and safety of treatment diabetic macular edema treated with intravitreal ziv-aflibercept as studies have shown that Ziv-aflibercept does not cause retinal pigment epithelial toxicity and to study it cost effectiveness.
openaire +1 more source
Anti-VEGF drugs compared with laser photocoagulation for the treatment of diabetic retinopathy: a systematic review and meta-analysis [PDF]
Background: Diabetic retinopathy is a major cause of sight loss in people with diabetes. The most severe form, proliferative diabetic retinopathy, carries a high risk of vision loss, vitreous haemorrhage, macular oedema and other harms.
Bojke L +12 more
core +1 more source
Anti-VEGF drugs compared with laser photocoagulation for the treatment of proliferative diabetic retinopathy: a systematic review and individual participant data meta-analysis [PDF]
Background: Proliferative diabetic retinopathy is a major cause of sight loss in people with diabetes, with a high risk of vitreous haemorrhage, tractional retinal detachment and other complications. Panretinal photocoagulation is the primary established
Bojke L +14 more
core +1 more source
Cancer Metastases to the Liver: Mechanisms of Tumor Cell Colonization
PharmaceuticalsThe liver is one of the most common sites for metastasis, which involves the spread from primary tumors to surrounding organs and tissues in the human body.
Wiktoria Andryszkiewicz +7 more
doaj +1 more source
Efficacy of intravitreal ziv-aflibercept in patients with macular edema following retinal vein occlusion in Korle-Bu Teaching Hospital, Ghana: a retrospective case series. [PDF]
Int Ophthalmol, 2021 Braimah IZ, Agyabeng K, Amoaku WM.
europepmc +1 more source
Emerging drugs for the treatment of diabetic retinopathy [PDF]
, 2020 Caccioppo, Andrea +4 more
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