Results 121 to 130 of about 19,002 (159)

Comment on: Intravitreal ziv-aflibercept for recurrent macular edema secondary to central retinal venous occlusion

open access: yesIndian Journal of Ophthalmology, 2015
Alok Sen   +3 more
doaj   +1 more source

374 A phase IB trial of ziv-aflibercept plus pembrolizumab in patients with advanced solid tumors

open access: yesJournal for ImmunoTherapy of Cancer, 2021
Howard Streicher   +9 more
doaj   +1 more source

Intraperitoneal ziv-aflibercept effectively manages refractory ascites in colorectal cancer patients. [PDF]

open access: yesOncotarget, 2017
Lu CS   +11 more
europepmc   +1 more source

Preclinical Investigations of Intravitreal Ziv-Aflibercept

open access: yesOphthalmic Surgery Lasers and Imaging Retina, 2014
BACKGROUND AND OBJECTIVE: To investigate the retinal safety of intravitreal (IVT) ziv-aflibercept in rabbits. MATERIALS AND METHODS: Eighteen rabbits were given an IVT injection of ziv-aflibercept (25 mg/mL) or aflibercept (40 mg/mL) and examined by funduscopy, electroretinography ...
Michel Eid Farah   +2 more
exaly   +4 more sources

Intravitreal Ziv-Aflibercept: A Comprehensive Review

Seminars in Ophthalmology, 2019
Background: Age-related macular degeneration is the leading cause of blindness in adults over the age of 50 in the United States of America. Neovascular age-related macular degeneration (nAMD) is sight-threatening, but can be treated by three currently utilized, intravitreally administered drugs: aflibercept, bevacizumab, and ranibizumab.
Daniel Barmas-Alamdari   +2 more
exaly   +3 more sources

Analytical comparability assessment on glycosylation of ziv-aflibercept and the biosimilar candidate

International Journal of Biological Macromolecules, 2021
Ziv-aflibercept (aflibercept) is a recombinant fusion protein which combines the portions of human vascular endothelial growth factor receptors extracellular domains fused to the Fc portion of human IgG1. It is a highly sialylated glycoprotein with 5 N-glycosylation sites.
Qing Li, Huarong Xu, Yanhong Wang
exaly   +3 more sources

Long-term safety and efficacy of ziv-aflibercept in retinal diseases [PDF]

open access: yesBritish Journal of Ophthalmology, 2017
To investigate the long-term safety of intravitreal ziv-aflibercept in eyes receiving six or more intravitreal injections of ziv-aflibercept, an off-label substitute to the approved aflibercept.Consecutive patients with retinal disease receiving six or more of intravitreal 0.05 mL ziv-aflibercept (1.25 mg) injections were followed monthly in three ...
Ahmad M Mansour   +5 more
openaire   +3 more sources

INTRAVITREAL INJECTIONS OF ZIV-AFLIBERCEPT FOR DIABETIC MACULAR EDEMA

open access: yesRetina, 2016
Diabetic macular edema is the leading cause of blindness in young adults in developed countries. Beyond metabolic control, several therapies have been studied such as laser treatment and intravitreal injections of corticosteroids or anti-vascular endothelial growth factor drugs.
Gabriel Costa de, Andrade   +5 more
openaire   +3 more sources

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