Results 131 to 140 of about 14,464 (157)
Intraperitoneal ziv-aflibercept effectively manages refractory ascites in colorectal cancer patients. [PDF]
Oncotarget, 2017 Lu CS +11 more
europepmc +1 more source
Preclinical Investigations of Intravitreal Ziv-Aflibercept
Ophthalmic Surgery Lasers and Imaging Retina, 2014 BACKGROUND AND OBJECTIVE: To investigate the retinal safety of intravitreal (IVT) ziv-aflibercept in rabbits. MATERIALS AND METHODS: Eighteen rabbits were given an IVT injection of ziv-aflibercept (25 mg/mL) or aflibercept (40 mg/mL) and examined by funduscopy, electroretinography ...
João Rafael De Oliveira Dias +2 more
exaly +4 more sources
Medical Oncology, 2017 Routine clinical practice data often differ from clinical trials. This study describes real-world treatment patterns and effectiveness among patients with metastatic colorectal cancer (mCRC) receiving ziv-aflibercept in non-academic, community oncology ...
JASMINA I Ivanova +2 more
exaly +2 more sources
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Intravitreal Ziv-Aflibercept: A Comprehensive Review
Seminars in Ophthalmology, 2019Background: Age-related macular degeneration is the leading cause of blindness in adults over the age of 50 in the United States of America. Neovascular age-related macular degeneration (nAMD) is sight-threatening, but can be treated by three currently utilized, intravitreally administered drugs: aflibercept, bevacizumab, and ranibizumab.
Daniel Barmas-Alamdari +2 more
exaly +3 more sources
Analytical comparability assessment on glycosylation of ziv-aflibercept and the biosimilar candidate
International Journal of Biological Macromolecules, 2021Ziv-aflibercept (aflibercept) is a recombinant fusion protein which combines the portions of human vascular endothelial growth factor receptors extracellular domains fused to the Fc portion of human IgG1. It is a highly sialylated glycoprotein with 5 N-glycosylation sites.
Huarong Xu, Qing Li
exaly +3 more sources
Intravitreal Ziv-Aflibercept : Safety Analysis in Eyes Receiving More Than Ten Intravitreal Injections [PDF]
Seminars in Ophthalmology, 2020 Purpose: To report the ocular and systemic adverse events in eyes receiving ≥10 intravitreal ziv-aflibercept (IVZ) injections. Methods: Medical records of patients who received ≥10 IVZ for various chorioretinal conditions with minimum follow up period of
Sumit Randhir Singh +2 more
exaly +2 more sources
Ziv-aflibercept (Zaltrap) for the Treatment of Metastatic Colorectal Cancer
Annals of Pharmacotherapy, 2013Objective: Review pharmacology, pharmacokinetics, efficacy, and safety of ziv-aflibercept in combination with FOLFIRI for treatment of metastatic colorectal cancer (mCRC) resistant to or progressed following oxaliplatin-containing regimens. Data Sources: Articles indexed in PubMed (1948-August 2013), TOXLINE (2001-August 2013), and Google Scholar as ...
Scott L, Perkins, Sabrina W, Cole
openaire +2 more sources
SHORT-TERM SAFETY PROFILE OF INTRAVITREAL ZIV-AFLIBERCEPT
Retina, 2016To evaluate the safety of intravitreal ziv-aflibercept (Zaltrap) in the treatment choroidal neovascularization secondary to age-related macular degeneration.Eligible eyes with choroidal neovascularization secondary to age-related macular degeneration each received a single intravitreal injection of ziv-aflibercept. Comprehensive ophthalmic examinations
Jay, Chhablani +4 more
openaire +2 more sources
SHORT-TERM SAFETY OF 2 MG INTRAVITREAL ZIV-AFLIBERCEPT
Retina, 2017Purpose: To evaluate the safety of single intravitreal 2 mg ziv-aflibercept (0.08 mL) injections for the treatment of choroidal neovascular membranes (CNVM). Methods: Eyes with choroidal neovascular membranes because of several conditions each received single intravitreal injections
Jay, Chhablani +3 more
openaire +2 more sources