Results 111 to 120 of about 895 (134)
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Ziv-aflibercept: binding to more than VEGF-A—does more matter?

Nature Reviews Clinical Oncology, 2012
The VELOUR and VITAL studies recently demonstrated ziv-aflibercept improved overall survival in patients with metastatic colorectal cancer (mCRC), including those previously treated with bevacizumab, but did not improve overall survival in non-small-cell lung cancer.
Herbert Hurwitz   +2 more
exaly   +3 more sources

Long-term outcome of treat and extend intravitreal ziv-aflibercept therapy

British Journal of Ophthalmology, 2018
AimTo assess the 30-month outcome of treat and extend (TAE) intravitreal ziv-aflibercept therapy in eyes with macular diseases.MethodsIn this prospective study, consecutive subjects received intravitreal 0.05 mL ziv-aflibercept (1.25 mg) injections for various macular diseases. Outcome measures were best-corrected visual acuity (BCVA) (logarithm of the
Ahmad M, Mansour   +4 more
openaire   +2 more sources

Intravitreal Ziv-Aflibercept for Diabetic Macular Edema: 48-Week Outcomes

Ophthalmic Surgery, Lasers and Imaging Retina, 2018
BACKGROUND AND OBJECTIVE: To study the safety and efficacy of intravitreal injections of ziv-aflibercept (IVI-ZA) (Zaltrap; Sanofi-Aventis and Regeneron Pharmaceuticals, Tarrytown, NY) during a period of 48 weeks in patients with diabetic macular edema (DME).
Gabriel Costa, de Andrade   +5 more
openaire   +2 more sources

Safety and Efficacy of Ziv-Aflibercept in the Treatment of Refractory Diabetic Macular Edema

Ophthalmic Surgery, Lasers and Imaging Retina, 2017
BACKGROUND AND OBJECTIVE: To evaluate the safety and efficacy of ziv-aflibercept (Zaltrap; Sanofi-Aventis, Bridgewater, NJ/Regeneron Pharmaceuticals, Tarrytown, NY) in the treatment of refractory diabetic macular edema (DME). PATIENTS AND METHODS: Retrospective case series looking ...
Mohammed, Ashraf   +2 more
openaire   +2 more sources

Ziv-aflibercept: A novel angiogenesis inhibitor for the treatment of metastatic colorectal cancer

American Journal of Health-System Pharmacy, 2013
Abstract Purpose The pharmacology, pharmacokinetics, clinical efficacy, safety, and administration of ziv-aflibercept in combination therapy for metastatic colorectal cancer (mCRC) are reviewed. Summary Ziv-aflibercept (Zaltrap ...
Clement, Chung, Nisha, Pherwani
openaire   +2 more sources

INTRAVITREAL ZIV-AFLIBERCEPT FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

Retina, 2019
Purpose: To evaluate the 52-week safety and efficacy of intravitreal ziv-aflibercept in patients with neovascular age-related macular degeneration. Methods: All patients received three monthly intravitreal injections of 0.05 mL of ziv-aflibercept (1.25 mg) followed by a pro re nata ...
João R, de Oliveira Dias   +9 more
openaire   +2 more sources

Regression of Inflamed Pterygia by Frequent High-Dose Intralesional Ziv-Aflibercept

Cornea, 2017
Purpose: Intralesional single low-dose vascular endothelial growth factor antagonists have traditionally failed in causing regression of pterygia. The current pilot study investigates the role of high-dose repeated intralesional ziv-aflibercept in causing regression of inflamed or recurring pterygia.
openaire   +2 more sources

Stability study over time of clinical solutions of ziv-aflibercept prepared in infusion bags using a proper combination of physicochemical and functional strategies

Journal of Pharmaceutical and Biomedical Analysis, 2021
Salvador Casares-Atienza   +2 more
exaly  

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