Results 91 to 100 of about 1,663 (174)
Intravitreal Ziv-Aflibercept: Clinical Effects and Economic Impact
Asia-Pacific Journal of Ophthalmology, 2017 During the past decade, drugs that inhibit the actions of vascular endothelial growth factor (VEGF) have become standard-of-care treatment for a variety of chorioretinal vascular conditions. The off-label, intravitreal use of ziv-aflibercept (Zaltrap) has provided clinicians with an additional cost-effective drug.
Sumit Randhir, Singh +4 more
openaire +2 more sources
Neoplasia: An International Journal for Oncology Research, 2016 BACKGROUND & AIM: Aflibercept known as ziv-aflibercept in the United States is a soluble decoy receptor of both vascular endothelial growth factor (VEGF) receptor-1 and -2 known to inhibit the binding of VEGF and placental growth factor (PlGF) to VEGF ...
Takuji Torimura +11 more
doaj +1 more source
Toward Precision Medicine: Gene Therapy Applications in the Management of Uveal Melanoma
Cancer Reports, Volume 8, Issue 12, December 2025.ABSTRACT Background Uveal melanoma (UM) is the prevailing malignant tumor that develops within the eye in adults, and it has a bleak outlook because of the few treatment choices available and the high likelihood of returning after treatment. Currently, surgical intervention, radiation therapy, and a combination of both modalities are available ...
Alireza Azani +13 more
wiley +1 more source
Colorectal cancer: from the genetic model to posttranscriptional regulation by noncoding RNAs [PDF]
, 2017 Colorectal cancer is the third most common form of cancer in developed countries and, despite the improvements achieved in its treatment options, remains as one of the main causes of cancer-related death.
Calle Espinosa, Jorge +6 more
core +4 more sources
Natural products targeting tumour angiogenesis
British Journal of Pharmacology, Volume 182, Issue 10, Page 2094-2136, May 2025.Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu +2 more
wiley +1 more source
Therapeutic Advances in Ophthalmology, 2020 Purpose: To evaluate the combination of fundus autofluorescence results with several clinical and structural variables into mathematical indexes to enhance their ability to predict visual and anatomical changes after the antivascular endothelial growth ...
Sergio E. Hernández Da Mota +6 more
doaj +1 more source
Angiogenesis Inhibitors in Small Cell Lung Cancer
Frontiers in Oncology, 2021 Inhibition of angiogenesis has been demonstrated to be an efficacious strategy in treating several tumors. Vascular endothelial growth factor (VEGF) is the most important protein with proangiogenic functions and it is overexpressed in small cell lung ...
Agnese Montanino +14 more
doaj +1 more source
Animal Models and Experimental Medicine, Volume 7, Issue 5, Page 591-605, October 2024.Fisetin has been shown to exhibit significant impact on colorectal cancer (CRC) in animal models by targeting various cellular and molecular mechanisms. It inhibits the phosphorylation of Y‐box binding protein 1 and ribosomal S6 kinase and promotes the phosphorylation of extracellular signal‐regulated kinase 1/2 (ERK1/2), thereby disrupting the repair ...
Mohammad Yasin Zamanian +9 more
wiley +1 more source
A Novel Inhibitor Of Sirtuin: Elucidation Of Mode Of Action And Molecular Pathway In Colorectal Cancer Cell Line [PDF]
, 2017 Kanser kolon merupakan salah satu jenis kanser yang paling banyak didapati di seluruh dunia Colorectal cancer (CRC) is one of the most common types of cancer ...
Tan, Yi Jer
core
MedComm – Oncology, Volume 3, Issue 3, September 2024.Immune checkpoint therapy is the main means of cancer treatment. However, most patients develop strong resistance to it. Another cancer treatment is antiangiogenic therapy. It enhances tumor immune response. Gut microbes enhance the efficacy of immunotherapy. We hope that the three of them will be able to treat cancer together.
Jie Xu +4 more
wiley +1 more source