Results 111 to 120 of about 861 (122)
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INTRAVITREAL ZIV-AFLIBERCEPT FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

Retina, 2019
Purpose: To evaluate the 52-week safety and efficacy of intravitreal ziv-aflibercept in patients with neovascular age-related macular degeneration. Methods: All patients received three monthly intravitreal injections of 0.05 mL of ziv-aflibercept (1.25 mg) followed by a pro re nata ...
João R, de Oliveira Dias   +9 more
openaire   +2 more sources

INTRAVITREAL INJECTIONS OF ZIV-AFLIBERCEPT FOR DIABETIC MACULAR EDEMA

Retina, 2016
Diabetic macular edema is the leading cause of blindness in young adults in developed countries. Beyond metabolic control, several therapies have been studied such as laser treatment and intravitreal injections of corticosteroids or anti-vascular endothelial growth factor drugs.
Gabriel Costa de, Andrade   +5 more
openaire   +2 more sources

Long-term outcome of treat and extend intravitreal ziv-aflibercept therapy

British Journal of Ophthalmology, 2018
AimTo assess the 30-month outcome of treat and extend (TAE) intravitreal ziv-aflibercept therapy in eyes with macular diseases.MethodsIn this prospective study, consecutive subjects received intravitreal 0.05 mL ziv-aflibercept (1.25 mg) injections for various macular diseases. Outcome measures were best-corrected visual acuity (BCVA) (logarithm of the
Ahmad M, Mansour   +4 more
openaire   +2 more sources

Ziv-aflibercept: binding to more than VEGF-A—does more matter?

Nature Reviews Clinical Oncology, 2012
The VELOUR and VITAL studies recently demonstrated ziv-aflibercept improved overall survival in patients with metastatic colorectal cancer (mCRC), including those previously treated with bevacizumab, but did not improve overall survival in non-small-cell lung cancer.
Jeffrey M, Clarke, Herbert I, Hurwitz
openaire   +2 more sources

Long-term safety and efficacy of ziv-aflibercept in retinal diseases

British Journal of Ophthalmology, 2017
To investigate the long-term safety of intravitreal ziv-aflibercept in eyes receiving six or more intravitreal injections of ziv-aflibercept, an off-label substitute to the approved aflibercept.Consecutive patients with retinal disease receiving six or more of intravitreal 0.05 mL ziv-aflibercept (1.25 mg) injections were followed monthly in three ...
Ahmad M Mansour   +5 more
openaire   +2 more sources

Regression of Inflamed Pterygia by Frequent High-Dose Intralesional Ziv-Aflibercept

Cornea, 2017
Purpose: Intralesional single low-dose vascular endothelial growth factor antagonists have traditionally failed in causing regression of pterygia. The current pilot study investigates the role of high-dose repeated intralesional ziv-aflibercept in causing regression of inflamed or recurring pterygia.
openaire   +2 more sources

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