Intravitreal ziv-aflibercept for macular edema following retinal vein occlusion [PDF]
Clinical Ophthalmology, 2016 Remya Paulose,1 Jay Chhablani,1 Chintan J Dedhia,1 Michael W Stewart,2 Ahmad M Mansour3,4 1Smt. Kanuri Santhamma Centre for Vitreoretinal Diseases, LV Prasad Eye Institute, Hyderabad, India; 2Department of Ophthalmology, Mayo Clinic, Jacksonville, FL ...
Paulose R +4 more
doaj +9 more sources
Evaluation of aflibercept and ziv-aflibercept binding affinity to vascular endothelial growth factor, stability and sterility after compounding [PDF]
International Journal of Retina and Vitreous, 2018 Purpose To investigate the binding affinity, stability, and sterility of aflibercept and ziv-aflibercept to vascular endothelial growth factor (Holash et al. in Proc Natl Acad Sci USA 99(17):11393–11398, 2002.
Julia de Lima Farah +11 more
doaj +3 more sources
Bevacizumab versus ziv-aflibercept in branch retinal vein occlusion [PDF]
Indian Journal of Ophthalmology, 2019 Purpose: To compare the effectiveness of treatment with intravitreal bevacizumab (IVB) and ziv-aflibercept (IVZ) in patients with macular edema (ME) post-branch retinal vein occlusion (BRVO).
Imoro Z Braimah +4 more
doaj +4 more sources
Ziv-aflibercept in macular disease. [PDF]
Br J Ophthalmol, 2015 Aflibercept is an approved therapy for neovascular age-related macular degeneration (AMD) and diabetic macular oedema (DME). In vitro and in vivo studies did not detect toxicity to the retinal pigment epithelium cells using the approved cancer protein, ziv-aflibercept.
Mansour AM +3 more
europepmc +6 more sources
Intravitreal Ziv-Aflibercept in Treatment of Naïve Chronic Central Serous Chorioretinopathy Related Choroidal Neovascular Membrane [PDF]
Case Reports in Ophthalmological Medicine, 2017 Purpose. To study the effect and outcome of intravitreal Ziv-Aflibercept (IVZ) in treatment of Chronic Central Serous Chorioretinopathy (CSCR) related Choroidal Neovascular Membrane (CNVM). Methods.
Nishant Radke +3 more
doaj +3 more sources
Ziv-aflibercept in Diabetic Macular Edema: Relation of Subfoveal Choroidal Thickness with Visual and Anatomical Outcomes [PDF]
Journal of Ophthalmic & Vision Research, 2023 Purpose: To evaluate the effects of intravitreal ziv-aflibercept injections (IVZ) on subfoveal choroidal thickness (SCT) as well as on central macular thickness (CMT) and on best corrected visual acuity (BCVA) changes in eyes with center-involved ...
Siamak Moradian +5 more
doaj +2 more sources
A combination of suprachoroidal injection of triamcinolone using a custom-made needle and intravitreal Ziv-aflibercept every eight weeks to manage naïve/denovo central DME: a single-center retrospective case series [PDF]
International Journal of Retina and VitreousBackground Previous studies have shown promising effects of combining intravitreal bevacizumab and suprachoroidal injection of triamcinolone acetonide in treating DME. However, further research is needed.
Ameen Marashi +4 more
doaj +2 more sources
Comprehensive biophysical and functional study of ziv-aflibercept: characterization and forced degradation. [PDF]
Sci Rep, 2020 AbstractAflibercept (AFL) is an Fc fusion protein used in the treatment of colorectal cancers and different ophthalmological diseases. There are two medicines in which AFL is the active substance: Zaltrap and Eylea, referred as ziv-AFL and AFL respectively. No proper accelerated degradation studies were published on either AFL or ziv-AFL. These studies
Hermosilla J +6 more
europepmc +9 more sources
Toxicology Reports, 2023 Sulfur mustard (SM)-induced ocular injury is characterized by an acute inflammatory response that may become chronic or enter a latent phase with delayed pathology.
Ariel Gore +6 more
doaj +2 more sources
Comparison of antiangiogenic agents (ranibizumab, aflibercept, bevacizumab and ziv-aflibercept) in the therapeutic response to the exudative form of age-related macular degeneration according to the treat-and-extend protocol- true head-to-head study [PDF]
International Journal of Retina and VitreousPurpose To evaluate the structural and functional changes in eyes with neovascular age related macular degeneration (nAMD) in a real-world setting, using Treat and Extend protocol (T&E), comparing four antiangiogenic agents.
Tereza Kanadani +4 more
doaj +2 more sources