Results 51 to 60 of about 861 (122)
Dll4 blockade potentiates the anti-tumor effects of VEGF inhibition in renal cell carcinoma patient-derived xenografts. [PDF]
PLoS ONE, 2014 The Notch ligand Delta-like 4 (Dll4) is highly expressed in vascular endothelium and has been shown to play a pivotal role in regulating tumor angiogenesis.
Kiersten Marie Miles +12 more
doaj +1 more source
Erratum to "Osteonecrosis of the jaw associated with ziv-aflibercept". [PDF]
J Gastrointest Oncol, 2017 europepmc +3 more sources
Drug-induced immune-mediated thrombocytopenia due to bevacizumab-FOLFOX therapy: a case report [PDF]
Kosin Medical Journal, 2023 Drug-induced immune thrombocytopenia (DITP) is a very rare disease, with an estimated annual incidence of 10 cases per million. Oxaliplatin and irinotecan are widely used as chemotherapy for high-risk stage II and III colorectal cancer, and DITP has been
Minna Kim, Jong Hoon Lee, Jong Yoon Lee
doaj +1 more source
Cancer Medicine, Volume 9, Issue 4, Page 1485-1494, February 2020., 2020 Mismatch repair proficient colorectal cancer has been refractory to single‐agent programmed cell death protein 1 inhibitor therapy. Colon GVAX is an allogeneic, whole‐cell, granulocyte‐macrophage colony‐stimulating factor‐secreting cellular immunotherapy that induces T‐cell immunity against tumor‐associated antigens and has previously been studied in ...
Mark Yarchoan +19 more
wiley +1 more source
Safety of Intravitreal Injection of Biosimilar of Aflibercept in Rabbit Eyes
Journal of Ophthalmology, Volume 2020, Issue 1, 2020., 2020 Purpose. To assess the safety of biosimilar intravitreal aflibercept (CinnaGen Co., Iran) compared to the reference product (Eylea®; Bayer Schweiz AG, Zurich, Switzerland) in rabbit eyes through functional and histologic studies. Methods. Forty New Zealand albino rabbits were recruited to the study and were divided into four groups to be sacrificed at ...
Alireza Lashay +13 more
wiley +1 more source
Journal of Ophthalmology, Volume 2020, Issue 1, 2020., 2020 Purpose. To evaluate the ocular pharmacokinetic properties of subretinal conbercept injection in vitrectomized rabbit eyes and to compare them with those by intravitreal injection. Methods. The following groups of New Zealand white rabbits received conbercept injections (0.5 mg/0.05 ml): a subretinal group (subretinal injection in vitrectomized eyes ...
Teng-teng Yao +7 more
wiley +1 more source
Frontiers in Oncology, 2023 ObjectiveIt remains unclear what the best second-line treatment is for patients with small-cell lung cancer sensitive to previous platinum-based chemotherapy.MethodsWe systematically screened randomized controlled trials from several online databases ...
Hekai Shi +6 more
doaj +1 more source
The Oncologist, Volume 25, Issue 1, Page e75-e84, January 2020., 2020 Abstract Background Trifluridine and tipiracil (FTD + TPI) and regorafenib (REG) are approved treatments for the treatment of refractory metastatic colorectal cancer (mCRC). This study assesses adherence and duration of therapy with FTD + TPI versus REG and explores the effect of sequencing on adherence. Materials and Methods Adults diagnosed with mCRC
Anuj K. Patel +6 more
wiley +1 more source
Intravitreal Ziv-Aflibercept: Clinical Effects and Economic Impact
Asia-Pacific Journal of Ophthalmology, 2017 During the past decade, drugs that inhibit the actions of vascular endothelial growth factor (VEGF) have become standard-of-care treatment for a variety of chorioretinal vascular conditions. The off-label, intravitreal use of ziv-aflibercept (Zaltrap) has provided clinicians with an additional cost-effective drug.
Sumit Randhir, Singh +4 more
openaire +2 more sources
Comparison between ziv-aflibercept and ranibizumab for treatment of diabetic macular edema
Journal of the Egyptian Ophthalmological SocietyAim To evaluate safety and efficacy of ziv-aflibercept in comparison to ranibizumab for the treatment of diabetic macular edema (DME). Patients and methods A total of 84 patients (84 eyes) with DME and central macular thickness (CMT) greater than 350 μ ...
Abdalah S. Nasr +3 more
doaj +1 more source