ZO-1 boosts the in vitro self-renewal of pre-haematopoietic stem cells from OCT4-reprogrammed human hair follicle mesenchymal stem cells through cytoskeleton remodeling. [PDF]
Stem Cell Res TherRuan Y +7 more
europepmc +1 more source
AlignPCA‐2D: PCA‐reduced Euclidean vector alignment for 2D classification in cryo‐EM
Acta Crystallographica Section D, EarlyView.We introduce AlignPCA‐2D, a PCA‐space Euclidean alignment method for rapid and interpretable 2D classification of cryo‐EM particle images. The approach preserves essential structural variability while greatly reducing computational cost, offering a lightweight alternative to existing large‐scale cryo‐EM classification pipelines.Cryogenic electron ...
E. Ramírez-Aportela +6 more
wiley +1 more source
circRNA-PTPN4 mediated regulation of FOXO3 and ZO-1 expression: implications for blood-brain barrier integrity and cognitive function in uremic encephalopathy. [PDF]
Cell Biol ToxicolLiu Y, Qin Y, Zhang Y.
europepmc +1 more source
Microbiology and Immunology, EarlyView.ABSTRACT Chronic rhinosinusitis with nasal polyps (CRSwNP) exhibits pronounced endotypic heterogeneity, with macrophages serving as key drivers of sustained mucosal inflammation. In this study, we identify S100A9 as a macrophage‐derived alarmin that is markedly elevated in CRSwNP tissues.
Yunxiang Ji +5 more
wiley +1 more source
Fluvoxamine may reverse the decrease in filtering capacity that occurs in acute kidney injury by increasing IL-10 and ACE expressions and preserving AQ-2, AQ-4, CL-5, and ZO-1 expressions. [PDF]
Naunyn Schmiedebergs Arch PharmacolKarakuyu NF +6 more
europepmc +1 more source
Bactrian in Issyk‐Kushan Script: Additional Readings and Decipherments1
Transactions of the Philological Society, EarlyView.Abstract This article presents additional readings of several inscriptions written in the Issyk‐Kushan script, building on the improved system of sound values recently proposed by Sims‐Williams (2025b). We propose that some further lines of Dašt‐i Nāwur inscription DN III and parts of several other inscriptions can now be read as Bactrian, add new ...
Jakob Halfmann +3 more
wiley +1 more source
Cepharanthine maintains integrity of the blood-brain barrier (BBB) in stroke via the VEGF/VEGFR2/ZO-1 signaling pathway. [PDF]
Aging (Albany NY)Yang Y +6 more
europepmc +1 more source
There Is no First Phase of the Jespersen Cycle1
Transactions of the Philological Society, EarlyView.Abstract This paper challenges the traditional conception of the Jespersen Cycle by arguing that no ‘pure’ first phase of the cycle exists where a single negator operates without reinforcement. Drawing on historical data from Northern Italian dialects (Piedmontese, Lombard, Emilian), we demonstrate that emphatic negative structures systematically co ...
Tommaso Mattiuzzi, Cecilia Poletto
wiley +1 more source
Journal of Agricultural Economics, EarlyView.ABSTRACT The Carbon Border Adjustment Mechanism (CBAM), scheduled to become fully operational in 2026, is designed to complement the EU Emissions Trading System (ETS) by replacing free emission allowances and preventing carbon leakage to non‐EU regions. CBAM initially covers energy‐intensive sectors, including mineral nitrogen (N) fertiliser production.
Davit Stepanyan +6 more
wiley +1 more source