Results 191 to 200 of about 91,984 (280)

Oncogenic H‐Ras Reprograms Madin‐Darby Canine Kidney (MDCK) Cell‐Derived Midbody Remnant Proteome Following Epithelial‐Mesenchymal Transition

PROTEOMICS, EarlyView.
ABSTRACT Epithelial‐mesenchymal transition (EMT) is a fundamental, dynamic cellular process involved in embryonic development, metastasis, organ fibrosis, and tissue regeneration. To define the molecular landscape of secreted midbody remnants (MBRs) to the EMT process, a proteome analysis of MBRs released from Madin–Darby canine kidney (MDCK) cells and
Adnan Shafiq, Alin Rai, Rong Xu, Maoshan Chen, Wittaya Suwakulsiri, David W. Greening, Richard J. Simpson   +6 more
wiley   +1 more source

Delayed Administration of IGFBP7 Improved Bone Defect Healing via ZO-1 Dependent Vessel Stabilization. [PDF]

Adv Sci (Weinh)
Sun S, Li Y, Li Y, Niu Y, Hu Z, Deng C, Chen Y, Hu B, Huang Y, Deng X.   +9 more
europepmc   +1 more source

Windows of opportunity in subseasonal weather regime forecasting: A statistical–dynamical approach

Quarterly Journal of the Royal Meteorological Society, EarlyView.
This study explores how the atmospheric state at initialisation creates windows of opportunity for improving week 3 forecasts of weather regime activity. Greenland blocking activity increases following Madden–Julian Oscillation phases 7, 8, and 1 and weak stratospheric polar vortex states, revealing patterns exploitable by statistical models.
Fabian Mockert, Christian M. Grams, Sebastian Lerch, Julian Quinting   +3 more
wiley   +1 more source

Exceptionally poor and good medium‐range forecasts of the large‐scale circulation over Europe in ERA5 reforecasts

Quarterly Journal of the Royal Meteorological Society, EarlyView.
This study investigates year‐round exceptionally poor and good day‐6 forecasts of the 500‐hPa geopotential height field over Europe using 45 years of ERA5 reforecasts and applies a weather regime perspective to analyse large‐scale pattern evolution and regime transitions.
Seraphine Hauser, Steven M. Cavallo, Linus Magnusson, Jonathan E. Martin, David B. Parsons   +4 more
wiley   +1 more source

Cadmium Induces Vascular Endothelial Cell Detachment by Downregulating Claudin-5 and ZO-1 Levels. [PDF]

Int J Mol Sci
Hara T, Asatsu M, Yamagishi T, Ohata C, Funatsu H, Takahashi Y, Shirai M, Nakata C, Katayama H, Kaji T, Fujie T, Yamamoto C.   +11 more
europepmc   +1 more source

GNAQ-Regulated ZO-1 and ZO-2 Act as Tumor Suppressors by Modulating EMT Potential and Tumor-Repressive Microenvironment in Lung Cancer. [PDF]

Int J Mol Sci, 2023
Kim HS, Lee SI, Choi YR, Kim J, Eun JW, Song KS, Jeong JY.   +6 more
europepmc   +1 more source

Surface‐Embedded Ag@Multilayer Graphene for Photothermal‐Enhanced Superhydrophobic Anti‐Icing Coatings

Rare Metals, EarlyView.
ABSTRACT Harnessing solar energy for self‐heating presents an effective strategy to suppress surface ice formation. In this paper, we fabricated nano‐silver‐modified multilayer graphene sheets (Ag@MGs) that integrate photothermal and superhydrophobic properties for anti‐icing applications.
Yihan Zhang, Xiaoqiang Fan, Xinrui Li, Jiaxin Xu, Zhongpan Zhang, Yunyun Duan, Minhao Zhu, Binbin Zhang   +7 more
wiley   +1 more source

Cooperative Binding of SRSF3 to Structured 3'ss-α Exon RNA during α Exon Inclusion in the ZO-1 mRNA. [PDF]

Curr Issues Mol Biol, 2023
Ruiz-Luis TA, Ortuño-Pineda C, Galindo-Rosales JM, Saucedo-Cárdenas O, Valdés J.   +4 more
europepmc   +1 more source

Epigenetic Dysregulation of the NKX2‐1/SPDEF Axis Drives Persistent Goblet Cell Differentiation and Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease

Respirology, EarlyView.
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota, Keiko Kan‐o, Yumiko Ishii, Tomoaki Koga, Takeshi Sawada, Kei‐ichiro Yasunaga, Shingo Usuki, Tatsuya Katsuno, Shigesato Inoue, Tomohiro Ogawa, Akihiro Jo, Satoru Fukuyama, Mitsuyoshi Nakao, Hiroaki Ogata, Mizuho A. Kido, Sachiko Tsukita, Koichiro Matsumoto, Isamu Okamoto   +17 more
wiley   +1 more source

Tight junction proteins occludin and ZO-1 as regulators of epithelial proliferation and survival. [PDF]

Ann N Y Acad Sci, 2022
Kuo WT, Odenwald MA, Turner JR, Zuo L.
europepmc   +1 more source