Results 261 to 270 of about 27,376,677 (317)

circRNA-PTPN4 mediated regulation of FOXO3 and ZO-1 expression: implications for blood-brain barrier integrity and cognitive function in uremic encephalopathy. [PDF]

Cell Biol Toxicol
Liu Y, Qin Y, Zhang Y.
europepmc   +1 more source

Space biomedicine‐oriented bioink and biomimetic blood‒brain barrier

VIEW, EarlyView.
Bioinks and bioprinting play a pivotal role in the successful delivery of cell models and the fabrication of tissue models for space biomedicine research. This study investigated the effects of hypergravity and vibration on two‐dimensional adherent cells and three‐dimensional embedded cells and provided methods for storing hybrid bioink and high ...
Ranran Yan, Ge Gao, YuJuan Li, YuLin Deng   +3 more
wiley   +1 more source

Cepharanthine maintains integrity of the blood-brain barrier (BBB) in stroke via the VEGF/VEGFR2/ZO-1 signaling pathway. [PDF]

Aging (Albany NY)
Yang Y, Li C, Yang S, Zhang Z, Bai X, Tang H, Huang J.   +6 more
europepmc   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

immunoHuMiX: A personalizable gut‐on‐chip model for unraveling human microbiome–immune interactions

VIEW, EarlyView.
The study introduces a personalized gut model that brings together human immune cells and intestinal cells to better mimic how the body interacts with microbes. This system successfully maintained both human cells and a 17‐strain probiotic community, showing consistent immune responses across different donors.
Charlotte De Rudder, Kacy Greenhalgh, Joanna Baginska, Camille Martin‐Gallausiaux, Léa Grandmougin, Rémy Villette, Mara Lucchetti, Bérénice Hansen, Marek Ostaszewski, Viacheslav A. Petrov, Koji Atarashi, Lena Weidert, Audrey Frachet Bour, Dominik Ternes, Javier Ramiro‐Garcia, Antoine Malabirade, Takeshi Tanoue, Marc Mac Giolla Eain, Elisabeth Letellier, Matthew Barrett, Jérôme Lacombe, Frederic Zenhausern, Coralie Guérin, Markus Ollert, Carole Seguin‐Devaux, Kenya Honda, Paul Wilmes   +26 more
wiley   +1 more source

ZO-1 regulates the migration of mesenchymal stem cells in cooperation with α-catenin in response to breast tumor cells. [PDF]

Cell Death Discov
Park A, Choi S, Do J, Kim Y, Kim KS, Koh E, Park KS.   +6 more
europepmc   +1 more source

A secured cloud‐medical data sharing with A‐BRSA and Salp ‐Ant Lion Optimisation Algorithm

CAAI Transactions on Intelligence Technology, EarlyView.
Abstract Sharing medical data among healthcare providers, researchers, and patients is crucial for efficient healthcare services. Cloud‐assisted smart healthcare (s‐healthcare) systems have made it easier to store EHRs effectively. However, the traditional encryption algorithms used to secure this data can be vulnerable to attacks if the encryption key
Adel Binbusayyis, Abed Alanazi, Shtwai Alsubai, Areej Alasiry, Mehrez Marzougui, Abdullah Alqahtani, Mohemmed Sha, Muhammad Aslam   +7 more
wiley   +1 more source

Adaptive Metabolic Responses Facilitate Blood-Brain Barrier Repair in Ischemic Stroke via BHB-Mediated Epigenetic Modification of ZO-1 Expression. [PDF]

Adv Sci (Weinh)
Li R, Liu Y, Wu J, Chen X, Lu Q, Xia K, Liu C, Sui X, Liu Y, Wang Y, Qiu Y, Chen J, Wang Y, Li R, Ba Y, Fang J, Huang W, Lu Z, Li Y, Liao X, Xiang AP, Huang Y.   +21 more
europepmc   +1 more source

Alteration of small intestinal occludin and ZO‐1 expession in liver cirrhosis

Pathology International
Theodoros Voulgaris, Dina Tiniakos, Dimitrios Karagiannakis, Despoina Myoteri, Despoina Karandrea, Spilios Manolakopoulos, George Papatheodoridis, Jiannis Vlachogiannakos   +7 more
openaire   +3 more sources

Targeting Inflammatory Alarmin S100A9 Modulates Activation of Pro‐Inflammatory Macrophage to Protect Nasal Epithelial Cells From LPS‐Induced Epithelial–Mesenchymal Transition

Microbiology and Immunology, EarlyView.
ABSTRACT Chronic rhinosinusitis with nasal polyps (CRSwNP) exhibits pronounced endotypic heterogeneity, with macrophages serving as key drivers of sustained mucosal inflammation. In this study, we identify S100A9 as a macrophage‐derived alarmin that is markedly elevated in CRSwNP tissues.
Yunxiang Ji, Jia Luan, Fang Yuan, Zhao Wang, Ran Wei, Guangbin Sun   +5 more
wiley   +1 more source