Results 261 to 266 of about 17,751,190 (266)

The Tight Junction Protein ZO‐2 Blocks Cell Cycle Progression and Inhibits Cyclin D1 Expression

Annals of the New York Academy of Sciences, 2009
ZO‐2 is an adaptor protein of the tight junction that belongs to the MAGUK protein family. ZO‐2 is a dual localization protein that in sparse cultures is present at the cell borders and the nuclei, whereas in confluent cultures it is concentrated at the cell boundaries.
Lorenza, Gonzalez-Mariscal, Rocio, Tapia, Miriam, Huerta, Esther, Lopez-Bayghen   +3 more
openaire   +2 more sources

Tight junction protein zo-2 is differentially expressed in normal pancreatic ducts compared to human pancreatic adenocarcinoma

International Journal of Cancer, 1999
Differential display of hamster mRNA identified a fragment present in normal pancreatic duct cells that is not expressed in pancreatic duct carcinoma cells. Sequence analysis showed an 88% and 82% identity, respectively, to the cDNA of the canine and human tight junction zo-2 gene.
A, Chlenski, K V, Ketels, M S, Tsao, M S, Talamonti, M R, Anderson, R, Oyasu, D G, Scarpelli   +6 more
openaire   +2 more sources

[LIM protein KyoT2 interacts with human tight junction protein ZO-2-i3].

Yi chuan xue bao = Acta genetica Sinica, 2003
It was reported that LIM protein KyoT2 negatively regulated transcription by association with the RBP-J DNA-binding protein. Using yeast two-hybrid system with LIM protein KyoT2 as a bait, we have isolated an alternatively spliced form of human tight junction protein 2--ZO-2-i3.
Hong-Yan, Huang, Rong, Li, Qiang, Sun, Jian, Wang, Peng, Zhou, Hua, Han, Wan-Hui, Zhang   +6 more
openaire   +1 more source

A ZO ‐2 scaffolding mechanism regulates the Hippo signalling pathway

The FEBS Journal
Contact inhibition of proliferation is a critical cell density control mechanism governed by the Hippo signalling pathway. The biochemical signalling underlying cell density‐dependent cues regulating Hippo signalling and its downstream effectors, YAP, remains poorly understood.
Olivia Xuan Liu, Lester Bocheng Lin, Soumya Bunk, Tiweng Chew, Selwin K. Wu, Fumio Motegi, Boon Chuan Low   +6 more
openaire   +2 more sources

Intracellular Traffic and Non-canonical Roles of ZO-2 Protein

2022
Lorenza González-Mariscal, Diana Cristina Pinto-Dueñas, Christian Hernández-Guzmán, Helios Gallego-Gutiérrez, Laura González-González, Misael Cano-Cortina   +5 more
openaire   +1 more source

Combined Deletion of Hepatic Zo-1 and Zo-2 Induces Loss of Bile Ducts

Journal of Hepatology, 2016
J. Xu, N. Van Hul, M. Caldez, M. Dewhurst, P. Kaldis, W. Hunziker   +5 more
openaire   +1 more source