Results 41 to 50 of about 22,649 (238)

Assessment of the Impact of Zoledronic Acid on Ovariectomized Osteoporosis Model Using Micro-CT Scanning. [PDF]

PLoS ONE, 2015
Prompted by preliminary findings, this study was conducted to investigate the impact of zoledronic acid on the cancellous bone microstructure and its effect on the level of β-catenin in a mouse model of postmenopausal osteoporosis.96 8-week-old specific ...
Bo Shuai, Lin Shen, Yanping Yang, Chen Ma, Rui Zhu, Xiaojuan Xu   +5 more
doaj   +1 more source

The effects of carboxylic acids on the aqueous dispersion and electrophoretic deposition of ZrO2 [PDF]

Journal of the European Ceramic Society, Volume 32, Issue 1, 2012, Pages 235-244, 2013
The agglomeration, electrokinetic properties and electrophoretic deposition behaviour of aqueous suspensions of ZrO2 with carboxylic acid additives were studied in comparison with conventional pH adjustment. It was found that citric acid imparted negative zeta-potential values and electrosteric stabilisation to particles in suspensions at all pH levels.
arxiv   +1 more source

Breast-Cancer Adjuvant Therapy with Zoledronic Acid [PDF]

New England Journal of Medicine, 2011
BACKGROUND Data suggest that the adjuvant use of bisphosphonates reduces rates of recurrence and death in patients with early-stage breast cancer. We conducted a study to determine whether treatment with zoledronic acid, in addition to standard adjuvant therapy, would improve disease outcomes in such patients.
Bundred, Nigel, Coleman, Robert E., Marshall, Helen, Cameron, David, Dodwell, David, Burkinshaw, Roger, Keane, Maccon, Gil, Miguel, Houston, Stephen J., Grieve, Robert J., Barrett-Lee, Peter J., Ritchie, Diana, Pugh, Julia, Gaunt, Claire, Rea, Una, Peterson, Jennifer, Davies, Claire, Hiley, Victoria, Gregory, Walter, Bell, Richard   +19 more
openaire   +4 more sources

Pain Assessment in Osteoarthritis: Present Practices and Future Prospects Including the Use of Biomarkers and Wearable Technologies, and AI‐Driven Personalized Medicine

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Osteoarthritis (OA) is a highly prevalent chronic joint disorder affecting ~600 million individuals worldwide and is characterized by complex pain mechanisms that significantly impair patient quality of life. Challenges exist in accurately assessing and measuring pain in OA due to variations in pain perception among individuals and the ...
Shujaa T. Khan, Nick Huffman, Xiaojuan Li, Anukriti Sharma, Carl S. Winalski, Eric T. Ricchetti, Kathleen Derwin, Suneel S. Apte, Daniel Rotroff, Carl Y. Saab, Nicolas S. Piuzzi   +10 more
wiley   +1 more source

Acute unilateral anterior uveitis following zoledronic acid infusion: A case report

SAGE Open Medical Case Reports, 2020
Bisphosphonates are widely used to treat several clinical conditions. Zoledronic acid is one of this class, commonly used for the treatment and prevention of osteoporosis, hypercalcemia of malignancy, Paget’s disease, and multiple myeloma.
Kiruththihan Anandasayanan, Muthusamy Malaravan, Navaneethakrishnan Suganthan   +2 more
doaj   +1 more source

Nature's Starships. I. Observed Abundances and Relative Frequencies of Amino Acids in Meteorites [PDF]

, 2014
The class of meteorites called carbonaceous chondrites are examples of material from the solar system which have been relatively unchanged from the time of their initial formation. These meteorites have been classified according to the temperatures and physical conditions of their parent planetesimals.
arxiv   +1 more source

Peri‐implant inflammation increases the risk of osteonecrosis in mice treated with bisphosphonate

Journal of Periodontology, EarlyView.
Abstract Background Bisphosphonates (BPs) are effective in managing bone diseases due to their anti‐resorptive properties but are linked to medication‐related osteonecrosis of the jaw (MRONJ), particularly concerning dental implants. This study explored the combined impact of ligature‐induced peri‐implant inflammation and zoledronic acid (ZA), a BP ...
Ana Bujila, Davi N. A. Silva, Sepehr Monajemzadeh, Taciane M. da Silveira, Naseim Elzakra, Maísa Casarin, Kimberly Flores, Clara Magyar, Julie Marchesan, Reuben Kim, Sotirios Tetradis, Flavia Q. Pirih   +11 more
wiley   +1 more source

Lessons learned from long-term side effects after zoledronic acid infusion following denosumab treatment: a case report and review of the literature

Journal of Medical Case Reports, 2022
Background Zoledronic acid is an intravenous, highly potent aminobisphosphonate for use in patients with primary or secondary osteoporosis. Zoledronic acid-induced prolonged side-effects are well known and quite common.
Ilona Nurmi-Lüthje, Peter Lüthje
doaj   +1 more source

A Preliminary Study on the Therapeutic Role of γδT Cells in Triple‐Negative Breast Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study was aimed to elucidate the cytotoxic effects of γδT cells on triple‐negative breast cancer (TNBC) cells and assess their antitumor efficacy in a mouse xenograft model. Furthermore, the underlying mechanisms of γδT cell action on TNBC were explored.
Shi Qiu, Qin‐Yu Han, Xian Zhao, Wen‐Jing Li, Xiang‐Qi Li   +4 more
wiley   +1 more source

Comparison of antiresorptive agents in the treatment of osteoporosis in older adults

Cukurova Medical Journal, 2022
Purpose: There are few studies comparing the effectiveness of anti-osteoporotic drugs among elderly population. In this study, we aimed to compare the effectiveness of alendronate, zoledronic acid, and denosumab in older adults. Materials and Methods: A
Zeynel Abidin Öztürk, Sencer Ganidağlı, Eyyüp Murat Efendioğlu, Ahmet Çiğiloğlu   +3 more
doaj   +1 more source