Results 91 to 100 of about 167,100,566 (339)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Proximity as a Window into the Zone of Proximal Development

Literacy Information and Computer Education Journal, 2018
Jacobs, BP orcid:0000-0002-1848-9356 ; The Zone of Proximal Development (ZPD) is one of the most widely accepted concepts in education but new research using digital technologies has shown that the co-construction of knowledge in the ZPD can also provide a window into the process of conceptual consolidation.
Jacobs, Brendan P, Usher, Adam
openaire   +2 more sources

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Vygotsky’s Zone Of Proximal Development and The Students’ Progress in Learning (A Heutagogcal Bibliographical Review)

, 2020
Inspired by the belief that Man’s power to change himself, that is, to learn, is perhaps the most impressive thing about him, the present study employed library research with a notated bibliography to highlight the pedagogical philosophy behind Vygotsky ...
I. W. Lasmawan, I. Budiarta
semanticscholar   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Zone of Proximal Development and Scaffolding Online

, 2009
While developing our courses, we realized the importance of the zone of proximal development (Vygotsky, 1978) in supporting our students. Learners’ experiences and backgrounds influence the learning process by bringing together the current learning ...
Andrea R. Bilics, Binta Colley, Carol M. Lerch   +2 more
core   +1 more source

Automated Hand Flexor Tendon–Thickness Measurement in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) can affect flexor tendons, contributing to hand function problems and reduced quality of life. Tendon changes are currently assessed with ultrasonography and measured manually, a time‐consuming process prone to interobserver variability.
Mark Greveling, Ties van het Erve, Yvette van de Berg, Simon Mastbergen, Julia Spierings   +4 more
wiley   +1 more source

Intuitive to Strategic Translanguaging: Insights From Vietnamese EFL Classrooms

Profile: Issues in Teachers' Professional Development
This article reports a qualitative case study on the translanguaging practices of Vietnamese English-as-a-foreign-language (EFL) educators and explores the mechanisms behind individual differences in their practices through an integrative cultural ...
Ngo Cong-Lem
doaj   +1 more source

Implications of Vygotsky’s sociocultural theory for second language (L2) assessment

Cogent Education, 2016
Dynamic assessment (DA) research, still in its infancy, takes its roots from Vygotsky’s concept of zone of proximal development (ZPD) to account for learner’s developmental process.
Karim Shabani
doaj   +1 more source