Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley +1 more source
Evaluating osseointegration, bone remodeling and osteolysis after total wrist arthroplasty using photon-counting detector CT. [PDF]
Kämmerling N +5 more
europepmc +1 more source
Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian +12 more
wiley +1 more source
Proximal Humerus Fractures - A Contemporary Narrative Review of Management Strategies. [PDF]
Baig U, Balbisi B, Patel R, Makki D.
europepmc +1 more source
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong +6 more
wiley +1 more source
Intraoperative Cardiac Arrest during Zone 0 Thoracic Endovascular Aortic Repair in a Post-Coronary Artery Bypass Grafting Patient with Bilateral Internal Thoracic Artery Grafts. [PDF]
Miyazawa K +4 more
europepmc +1 more source
A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg +16 more
wiley +1 more source
Interpreting the two-hour partial REBOA safety window: Physiologic context, monitoring limitations, and device-specific considerations. [PDF]
Russo RM +3 more
europepmc +1 more source
A bio‐inspired bidirectional‐winding origami platform enables scalable and programmable deployable structures. Double axial folding inspired by earwig hindwings and Flasher‐based hybridization create modular multilayer architectures with diverse attainable winding angles under fixed boundary conditions.
Wenyao Zhang +5 more
wiley +1 more source
The formation mechanism of the Liantang trough in Qiaojia County along the Jinsha River. [PDF]
Song L, Shang Y, Wang Y, Chang Z.
europepmc +1 more source

