Results 71 to 80 of about 12,742 (223)

Audit of use of stiripentol in adults with Dravet syndrome [PDF]

, 2016
OBJECTIVES: There are very few data available in the literature on the use of stiripentol in adults with Dravet syndrome (DS). DS cases are increasingly recognized in adulthood, and more children with DS now survive to adulthood. The aim of the study was
Balestrini, S, Sisodiya, SM
core   +1 more source

Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis: A shared phenotype across brain‐expressed sodium channelopathies

Epilepsia, EarlyView.
Abstract Objective Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis (NDEEMA) represents the most severe end of the gain‐of‐function (GOF) SCN1A disorder spectrum. Sporadic cases of congenital arthrogryposis have also been reported in individuals with SCN2A‐, SCN3A‐, and SCN8A‐related developmental and ...
Sopio Gverdtsiteli, Sebastian Ortiz, Tobias Brünger, Francesca Furia, Carmen Barba, Trine Bjørg‐Hammer, Ingo Borggraefe, Roberto Caraballo, Sebahattin Cirak, Alberto Espeche, Walid Fazeli, Renzo Guerrini, Matias Juanes, Karin Kassahn, Maria Kinali, Johannes Krämer, Judith Kröll, Maria Concepción Miranda Herrero, Renske Oegema, Katrin Ounap, Oscar Peñuela, Konrad Platzer, Asuri Narayan Prasad, Aurora Pujol, Karit Reinson, Alfonso Represa, Eugenia Roza, Gabriela Reyes Valenzuela, Agustí Rodríguez‐Palmero, Suzanne Sallevelt, Maria Iciar Sanchez‐Albiusa, Ingrid E. Scheffer, Cory Smid, Carl E. Stafstrom, Eva‐Lena Stattin, Jen R. Suarez, Steffen Syrbe, Kette D. Valente, Matias Wagner, Saskia Wortmann, Elena Gardella, Dennis Lal, Andreas Brunklaus, Rikke S. Møller   +43 more
wiley   +1 more source

Data for zonisamide effect on length and weight of 14 day-old rat pups and abortion rate and day in refractory epileptic pregnant rats

Data in Brief, 2018
Length and weight of 14 day-old rat pups and also abortion rate and day on refractory epileptic pregnant rats after treatment with zonisamide (ZNS) are presented.
Reza Narenji Sani, Keivan Keramati, Niloufar Saberi, Melika Moezifar, Ali Mahdavi   +4 more
doaj   +1 more source

Upregulated Connexin 43 Induced by Loss-of-Functional S284L-Mutant α4 Subunit of Nicotinic ACh Receptor Contributes to Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy

Pharmaceuticals, 2020
To study the pathomechanism and pathophysiology of autosomal dominant sleep-related hypermotor epilepsy (ADSHE), this study determined functional abnormalities of glutamatergic transmission in the thalamocortical motor pathway, from the reticular ...
Kouji Fukuyama, Masashi Fukuzawa, Ruri Okubo, Motohiro Okada   +3 more
doaj   +1 more source

A case report: retigabine induced oral mucosal dyspigmentation of the hard palate [PDF]

, 2015
Background Dyspigmentation of the oral mucosa has a multitude of aetiological causes. Retigabine, a new antiepileptic drug, has the potential side effect of inducing a blue/purple pigmentation of the oral mucosa in addition to the skin, lips, nails and ...
Beacher, Nicholas G., Brodie, Martin J., Goodall, Christine   +2 more
core   +1 more source

Sodium‐glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real‐world cohort study

Epilepsia, EarlyView.
Abstract Objective Late onset epilepsy (LOE) is associated with substantial morbidity. Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) may exert neuroprotective effects. This study evaluated the association between SGLT2i and risk of LOE among older adults with type 2 diabetes mellitus.
Bing‐Hua Lin, Hui‐Min Huang, Hui‐An Lin, Sheng‐Feng Lin   +3 more
wiley   +1 more source

The effect of oral zonisamide treatment on serum phenobarbital concentrations in epileptic dogs

Frontiers in Veterinary Science
Zonisamide is used in dogs for the treatment of epileptic seizures. It is predominantly metabolised by CYP450 hepatic enzymes. When used concurrently with phenobarbital (PB), zonisamide clearance is increased and its elimination half-life decreases ...
Elizabeth Mahon, Oliver Marsh, Ane Uriarte, Fabio Stabile   +3 more
doaj   +1 more source

International Veterinary Epilepsy Task Force Consensus Proposal: Outcome of therapeutic interventions in canine and feline epilepsy [PDF]

, 2015
Common criteria for the diagnosis of drug resistance and the assessment of outcome are needed urgently as a prerequisite for standardized evaluation and reporting of individual therapeutic responses in canine epilepsy. Thus, we provide a proposal for the
A Neligan, A Tipold, A Wessmann, Akos Pakozdy, Andrea Fischer, Andrea Tipold, B Callaghan, BD Jovanovic, C Rundfeldt, CA Scorza, CE Stafstrom, CH Gullov, CL Gaskill, Clare Rusbridge, CM Eddy, CW Dewey, DM Boothe, E Ben-Menachem, E Bersan, E Faught, E Perucca, European-Medicines-Agency, G Jacobs, G Zaccara, H Potschka, HA Volk, HE Baird-Heinz, Heidrun Potschka, HJ Cross, Holger A Volk, I Olmez, J Weissl, JA French, JA French, JA Hanley, Jacques Penderis, JF Tellez-Zenteno, JH Rossmeisl, JY Chung, K Orito, Karen Muñana, Kaspar Matiasek, KR Munana, KR Munana, KR Munana, KS Wilcox, L Librizzi, L Rutherford, LK Lord, Luisa De Risio, M Berendt, M Berendt, M Charalambous, M Schwartz, M Sillanpaa, MB Westover, Mette Berendt, MG Neuman, Michael Podell, ML Miller, N Fredso, N Shihab, Ned Patterson, P Kwan, P Ryvlin, PA March, Paul Mandigers, R Monteiro, R Shankar, RE Levitski, RM Packer, Robyn Farquhar, S Balosso, S Balosso, S Klamer, S Steinmetz, SA Kube, SA Moore, Sam Long, Simon Platt, Sofie Bhatti, T Glauser, T Glauser, T Klopmann von, T Klopmann Von, T Pancotto, U Yilmaz, V Hülsmeyer, V Tang, Veronika Stein, W Löscher, WHOQOL-Group T, Wolfgang Löscher, Y Chang   +93 more
core   +7 more sources

Mental health of children with epilepsy in Ukraine during the war

Epilepsia, EarlyView.
Abstract Objective The ongoing conflict in Ukraine has created a severe humanitarian crisis, disproportionately affecting vulnerable populations such as children with chronic conditions. We set out to determine information about mental health in children with epilepsy in Ukraine affected by the conflict.
Volodymyr Kharytonov, J. Helen Cross, Andriy Dubenko, Samuel Wiebe, on behalf of the ILAE Emergency Task Force for Ukraine   +4 more
wiley   +1 more source

Paths for Improving Bevacizumab Available in 2018: The ADZT Regimen for Better Glioblastoma Treatment

Medical Sciences, 2018
During glioblastoma treatment, the pharmaceutical monoclonal antibody to vascular endothelial growth factor A, bevacizumab, has improved the quality of life and delayed progression for several months, but has not (or only marginally) prolonged overall ...
Richard E. Kast
doaj   +1 more source