Results 41 to 50 of about 29,714,140 (226)

Zonula occludens and nasal epithelial barrier integrity in allergic rhinitis [PDF]

, 2020
Allergic rhinitis (AR) is a common disease affecting 400 million of the population worldwide. Nasal epithelial cells form a barrier against the invasion of environmental pathogens. These nasal epithelial cells are connected together by tight junction (TJ)
Norasnieda Md Shukri, Noor Suryani Mohd Ashari, Kah Keng Wong, Che Othman Siti Sarah   +3 more
core   +1 more source

Expression of Endothelial NOX5 Alters the Integrity of the Blood-Brain Barrier and Causes Loss of Memory in Aging Mice

Antioxidants, 2021
Blood-Brain barrier (BBB) disruption is a hallmark of central nervous system (CNS) dysfunction, and oxidative stress is one of the molecular mechanisms that may underlie this process.
Adriana Cortés, Maite Solas, Álvaro Pejenaute, Miguel A. Abellanas, Marcos Garcia-Lacarte, Maria S. Aymerich, Javier Marqués, María J. Ramírez, Guillermo Zalba   +8 more
doaj   +1 more source

Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2 [PDF]

, 2007
Background: Tight junctions are required for epithelial barrier formation and participate in the regulation of signalling mechanisms that control proliferation and differentiation.
Aijaz Saima, Sanchez-Heras Elena, Balda, MS, Matter Karl, Matter, K, Balda Maria S, Sanchez-Heras, E, Aijaz, S   +7 more
core   +1 more source

The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density [PDF]

, 2003
Epithelial tight junctions regulate paracellular permeability, restrict apical/basolateral intramembrane diffusion of lipids, and have been proposed to participate in the control of epithelial cell proliferation and differentiation.
Balda, MS, Matter, K, Karl Matter, Garrett, MD, Michelle D. Garrett, Maria S. Balda   +5 more
core   +1 more source

Structural simplicity of the Zonula Occludens in the electrolyte secreting epithelium of the avian salt gland [PDF]

, 1979
The structure of the zonula occludens in the secretory epithelium of the salt gland of the domestic duck was determined by thin section and freeze-fracture electron microscopy. These glands secrete an effluent with a NaCl concentration four times that of
Riddle, Clara V., Ernst, Stephen A.
core   +1 more source

Cx43 and the Actin Cytoskeleton: Novel Roles and Implications for Cell-Cell Junction-Based Barrier Function Regulation

Biomolecules, 2020
Barrier function is a vital homeostatic mechanism employed by epithelial and endothelial tissue. Diseases across a wide range of tissue types involve dynamic changes in transcellular junctional complexes and the actin cytoskeleton in the regulation of ...
Randy E. Strauss, Robert G. Gourdie
doaj   +1 more source

Tear fluid levels of interleukin-6 and tight junction protein ZO-1 and their association with the course of bacterial keratitis in type 2 diabetes mellitus under martial law in Ukraine

Медична наука України
Relevance. Bacterial keratitis is one of the most common infectious diseases of the cornea and may lead to severe complications, persistent visual impairment, and disability. Aim.
Andrii Hudz, Solomiia Kadubets
doaj   +1 more source

The Cx43 Carboxyl-Terminal Mimetic Peptide αCT1 Protects Endothelial Barrier Function in a ZO1 Binding-Competent Manner

Biomolecules, 2021
The Cx43 carboxyl-terminus (CT) mimetic peptide, αCT1, originally designed to bind to Zonula Occludens 1 (ZO1) and thereby inhibit Cx43/ZO1 interaction, was used as a tool to probe the role of Cx43/ZO1 association in regulation of epithelial/endothelial ...
Randy E. Strauss, Louisa Mezache, Rengasayee Veeraraghavan, Robert G. Gourdie   +3 more
doaj   +1 more source

Decreased expression of zonula occludens-1 and occludin in the bladder urothelium of patients with interstitial cystitis/painful bladder syndrome

Journal of the Formosan Medical Association, 2014
Unique barrier properties of the urothelial surface membrane permit urine storage without contents leak into the bloodstream. Previous reports suggested that the bladder urothelial barrier might be compromised in interstitial cystitis/painful bladder ...
Jane-Dar Lee, Ming-Huei Lee
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source