Results 111 to 120 of about 29,405 (257)

Shuxuetong injection protects cerebral microvascular endothelial cells against oxygen-glucose deprivation reperfusion

open access: yesNeural Regeneration Research, 2019
Shuxuetong injection composed of leech (Hirudo nipponica Whitman) and earthworm (Pheretima aspergillum) has been used for the clinical treatment of acute stroke for many years in China.
Zuo-Yan Sun   +8 more
doaj   +1 more source

Mechanisms regulating intestinal barrier integrity and its pathological implications [PDF]

open access: yes, 2018
The gastrointestinal tract is a specialized organ in which dynamic interactions between host cells and the complex environment occur in addition to food digestion.
CHAITHANYA, LAKSHMI CHELAKKOT GOVINDALAYA   +2 more
core   +1 more source

Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1

open access: yesOncology Letters, 2018
Zinc finger protein 668 (ZNF668) is a recently discovered protein and its expression levels, as well as its involvement in the invasion and metastasis of non-small cell lung cancer (NSCLC), are largely unknown. In the present study, immunohistochemical analysis demonstrated that ZNF668 protein expression was decreased in lung tumors (51/167, 30.5 ...
Xiupeng, Zhang   +7 more
openaire   +3 more sources

Spatial Overlap of Claudin- and Phosphatidylinositol Phosphate-Binding Sites on the First PDZ Domain of Zonula Occludens 1 Studied by NMR

open access: yesMolecules, 2018
Background: The tight junction is an intercellular adhesion complex composed of claudins (CLDs), occludin, and the scaffolding proteins zonula occludens 1 (ZO-1) and its two paralogs ZO-2 and ZO-3.
Hidekazu Hiroaki   +7 more
doaj   +1 more source

Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation. [PDF]

open access: yes, 2012
International audienceABSTRACT: The Blood--brain barrier (BBB), present at the level of the endothelium of cerebral blood vessels, selectively restricts the blood-to-brain paracellular diffusion of compounds; it is mandatory for cerebral homeostasis and ...
Artus, Cédric   +4 more
core   +4 more sources

Zonula Occludens-1 Is a Scaffolding Protein for Signaling Molecules [PDF]

open access: yesJournal of Biological Chemistry, 2002
Tobias N. Meyer   +2 more
openaire   +1 more source

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

open access: yesiNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang   +7 more
wiley   +1 more source

Molecular And Immunological Characteristics Of Vibrio Cholerae And Vibrio Alginolyticus [PDF]

open access: yes, 2000
Twenty isolates of Vibrio cholerae and four isolates of Vibrio alginolyticus used in this study were identified using the conventional biochemical tests.
Neela, Vasanthakumari
core  

Expression of Zonula Occludens-1 and Claudin-1 Proteins in Japanese Quails Testis

open access: yesVeterinary Sciences and Practices, 2023
İlknur ÜNDAĞ, Hasan Hüseyin DÖNMEZ
openaire   +2 more sources

Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood–brain barrier breakdown in vivo

open access: yesNeuroscience, 1998
The tight junctions found between cerebral vascular endothelial cells form the basis of the blood-brain barrier. Breakdown of the blood-brain barrier is a feature of a variety of CNS pathologies that are characterized by extensive leucocyte recruitment, such as multiple sclerosis and stroke. The molecular mechanisms associated with opening of the blood-
Bolton, S.J., Anthony, D.C., Perry, V.H.
openaire   +4 more sources

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