Regulation of claudin/zonula occludens-1 complexes by hetero-claudin interactions. [PDF]
Alcohol abuse is a risk factor for acute respiratory distress syndrome, flooding of the lungs due to compromised barrier function. Here the authors report that alcohol upregulates claudin-5 that is then recruited to tight junctions in alveolar epithelial
Schlingmann B +9 more
europepmc +2 more sources
Dietary ethylenediamine dihydroiodide improves intestinal health in Cherry Valley ducks
: This study investigated the effect of ethylenediamine dihydroiodide (EDDI) on the growth performance, thyroid function, immune function, intestinal development, intestinal permeability, intestinal barrier functions and microbial characteristics of ...
Yueqin Xie +10 more
doaj +1 more source
Confocal imaging dataset to assess endothelial cell orientation during extreme glucose conditions
Measurement(s) nucleus • F-actin • zonula occludens 1 Technology Type(s) confocal microscopy Factor Type(s) line width • medium glucose concentration Sample Characteristic - Organism Mus musculus Machine-accessible metadata file describing the reported ...
Ana María Porras Hernández +4 more
doaj +1 more source
Protects Porcine Intestinal Barrier from Deoxynivalenol via Improved Zonula Occludens-1 Expression [PDF]
Intestinal epithelial cells (IECs) forming the barrier for the first-line of protection are interconnected by tight junction (TJ) proteins. TJ alteration results in impaired barrier function, which causes potentially excessive inflammation leading to ...
Min Jeong Gu +4 more
doaj +1 more source
High resolution immunoinformatic profiling of Zonula occludens toxin reveals a conserved multiepitope vaccine candidate in <i>Acinetobacter baumannii</i>. [PDF]
Acinetobacter baumannii is a multidrug-resistant (MDR) nosocomial pathogen associated with exceptionally high mortality, underscoring the urgent need for immune-based strategies that operate independently of antibiotic susceptibility.
Benyamini P.
europepmc +2 more sources
Increased systemic zonula occludens 1 associated with inflammation and independent biomarker in patients with hepatocellular carcinoma. [PDF]
Background Hepatocellular carcinoma (HCC) is a frequent type of primary liver cancer, and its prevalence is increasing worldwide. Indeed, the underlying molecular mechanism is not well understood. Previous studies have shown evidence that tight junction (
Ram AK, Pottakat B, Vairappan B.
europepmc +2 more sources
Effect of Changes in Photoperiods on Melatonin Expression and Gut Health Parameters in Laying Ducks
We investigated the effect of photoperiod on ileal morphology, barrier function, short-chain fatty acid (SCFA) contents, microbial flora, melatonin expression, and synthesis in laying ducks.
Yao-ming Cui +7 more
doaj +1 more source
IntroductionFermented egg-milk peptides (FEMPs) could enhance the colon-intestinal barrier and upgrade the expression of zonula occludens-1 and mucin 2.
Siwen Lyu +9 more
doaj +1 more source
Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins. [PDF]
The molecular seal between epithelial cells, called the tight junction (TJ), is built by several membrane proteins, with claudins playing the most prominent role.
Nomme J +6 more
europepmc +2 more sources
Objectives: The non-O1/non-O139 Vibrio cholerae caused outbreaks or sporadic cases of gastroenteritis that was rarely seen in good sanitary condition. It was described a case of systemic multiple organ lesions that worsened because of non-O1/non-O139 V ...
Ying Zhao +9 more
doaj +1 more source

