<i>Lactobacillus johnsonii</i> Alleviates Immune Checkpoint Inhibitor-Associated Colitis by Modulating Macrophage Polarization, Th1/Treg Cell Balance, and Intestinal Barrier Function via the Tryptophan Metabolism-AhR Pathway. [PDF]
J Agric Food ChemLiang W +5 more
europepmc +1 more source
Porcine iPSC-Derived Intestinal Cells as a High-Fidelity Platform for PEDV Pathogenesis. [PDF]
Animals (Basel)Muangthong T +6 more
europepmc +1 more source
Probiotic lactic acid bacterial strains MG4693 and MG5474 alleviate atopic dermatitis by enhancing intestinal barrier integrity and modulating the immune system. [PDF]
Food Nutr ResYoon W +4 more
europepmc +1 more source
Silphium perfoliatum flavonoids alleviate LPS-induced injury via enhancing intestinal antioxidant capacity, barrier function, and regulating cecal microbiota in broilers. [PDF]
Poult SciLiu G +8 more
europepmc +1 more source
The PDZ2 domain of zonula occludens-1 and -2 is a phosphoinositide binding domain [PDF]
Cellular and Molecular Life Sciences, 2009 Zonula occludens proteins (ZO) are postsynaptic density protein-95 discs large-zonula occludens (PDZ) domain-containing proteins that play a fundamental role in the assembly of tight junctions and establishment of cell polarity. Here, we show that the second PDZ domain of ZO-1 and ZO-2 binds phosphoinositides (PtdInsP) and we identified critical ...
Hui Lu +2 more
exaly +4 more sources
Zonula occludens-1 (ZO-1) is involved in morula to blastocyst transformation in the mouse [PDF]
Developmental Biology, 2008 It is unknown whether or not tight junction formation plays any role in morula to blastocyst transformation that is associated with development of polarized trophoblast cells and fluid accumulation. Tight junctions are a hallmark of polarized epithelial cells and zonula occludens-1 (ZO-1) is a known key regulator of tight junction formation.
Jeff Reese +2 more
exaly +4 more sources
Association of connexin36 and zonula occludens-1 with zonula occludens-2 and the transcription factor zonula occludens-1-associated nucleic acid-binding protein at neuronal gap junctions in rodent retina [PDF]
Neuroscience, 2006 Most gap junctions between neurons in mammalian retina contain abundant connexin36, often in association with the scaffolding protein zonula occludens-1. We now investigate co-association of connexin36, zonula occludens-1, zonula occludens-2 and Y-box transcription factor 3 (zonula occludens-1-associated nucleic acid-binding protein) in mouse and rat ...
Xinbo Li, James Imre Nagy, John Rash
exaly +3 more sources
Telmisartan Increases the Permeability of Endothelial Cells through Zonula Occludens-1
Biological and Pharmaceutical Bulletin, 2009 Angiotensin receptor-1 blockers (ARBs) have been used for the treatment of atherosclerosis. Tight junctions are very important in the regulation of cellular permeability which may have a profound role in atherosclerosis. The relationship between them is unresolved.
Yihua Wu, Chang Bian
exaly +4 more sources
Zonula Occludens‐1 and ‐2 Are Cytosolic Scaffolds That Regulate the Assembly of Cellular Junctions
Annals of the New York Academy of Sciences, 2009 The integrity of the tight junction barrier in epithelial and endothelial cells is critical to human health, but we still lack a detailed mechanistic knowledge of how the barrier is formed during development or responds to pathological and pharmacological insults. This limits our understanding of barrier dysfunction in disease and slows the development
James Anderson, Alan S Fanning
exaly +4 more sources