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Docosahexaenoic acid (DHA) is a long-chain, highly unsaturated omega-3 (n-3) fatty acid. It has a structure that gives it unique physical and functional properties. DHA is metabolically related to other n-3 fatty acids: it can be synthesised from the plant essential fatty acid α-linolenic acid (ALA).
P. Calder
semanticscholar +13 more sources
Docosahexaenoic Acid and Cognition throughout the Lifespan [PDF]
Docosahexaenoic acid (DHA) is the predominant omega-3 (n-3) polyunsaturated fatty acid (PUFA) found in the brain and can affect neurological function by modulating signal transduction pathways, neurotransmission, neurogenesis, myelination, membrane ...
M. Weiser, C. Butt, M. Mohajeri
semanticscholar +4 more sources
Arachidonic Acid and Docosahexaenoic Acid Metabolites in the Airways of Adults With Cystic Fibrosis: Effect of Docosahexaenoic Acid Supplementation [PDF]
Cystic fibrosis (CF) is an autosomal recessive disorder, caused by genetic mutations in CF transmembrane conductance regulator protein. Several reports have indicated the presence of specific fatty acid alterations in CF patients, most notably decreased ...
Elisabetta Teopompi+13 more
doaj +7 more sources
Effect of dietary docosahexaenoic acid on biosynthesis of docosahexaenoic acid from alpha-linolenic acid in young ratss⃞ [PDF]
Docosahexaenoic acid (DHA), a crucial nervous system n-3 PUFA, may be obtained in the diet or synthesized in vivo from dietary α-linolenic acid (LNA).
James C. DeMar, Jr.+4 more
doaj +4 more sources
Docosahexaenoic acid neurolipidomics [PDF]
Mediator lipidomics is a field of study concerned with the characterization, structural elucidation and bioactivity of lipid derivatives actively generated by enzymatic activity. It is well known that omega-3 fatty acids are beneficial for brain function.
Nicolas G. Bazan, Tiffany D. Niemoller
openaire +3 more sources
Docosahexaenoic Acid and Preterm Birth [PDF]
Preterm birth accounts for more than 85% of all perinatal complications and deaths. There are many short- and long-term consequences of being born too soon. These infants often require intensive care and are at increased risk of early morbidities often with life-long sequelae.
Makrides, M., Best, K.
openaire +3 more sources
Maternal Docosahexaenoic Acid Status during Pregnancy and Its Impact on Infant Neurodevelopment
Dietary components are essential for the structural and functional development of the brain. Among these, docosahexaenoic acid, 22:6n-3 (DHA), is critically necessary for the structure and development of the growing fetal brain in utero. DHA is the major
Sanjay Basak, Rahul Mallick, A. Duttaroy
semanticscholar +1 more source
Background: Currently, 1–2% of all prosthetic joint surgeries are followed by an infection. These infections cause approximately 4% of deaths in the first year after surgery, while the 5-year mortality rate is up to 21%.
Christopher Spiegel+2 more
doaj +1 more source
The essentiality of arachidonic acid and docosahexaenoic acid [PDF]
The purpose of this review is to correlate the clinical finding that patients receiving parenteral nutrition with a fish oil-based lipid emulsion do not develop essential fatty acid deficiency (EFAD) with an experimental murine model, thus showing that arachidonic acid (AA) and docosahexaenoic acid (DHA) are likely to be the essential fatty acids ...
Mark Puder+4 more
openaire +3 more sources
In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang+6 more
wiley +1 more source