The core and accessory genomes of Burkholderia pseudomallei: implications for human melioidosis. [PDF]
PLoS Pathogens, 2008 Natural isolates of Burkholderia pseudomallei (Bp), the causative agent of melioidosis, can exhibit significant ecological flexibility that is likely reflective of a dynamic genome. Using whole-genome Bp microarrays, we examined patterns of gene presence
Siew Hoon Sim +16 more
doaj +1 more source
Bacterial microevolution and the Pangenome [PDF]
, 2020 The comparison of multiple genome sequences sampled from a bacterial population reveals considerable diversity in both the core and the accessory parts of the pangenome.
A Bankevich +68 more
core +1 more source
mBio, 2021 SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19), is an RNA virus with a large genome that encodes multiple accessory proteins.
Amin Addetia +11 more
doaj +1 more source
Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria
BMC Genomics, 2020 Background Antagonistic co-evolution can drive rapid adaptation in pathogens and shape genome architecture. Comparative genome analyses of several fungal pathogens revealed highly variable genomes, for many species characterized by specific repeat-rich ...
Alice Feurtey +9 more
doaj +1 more source
Pan-Genome Analysis Reveals Functional Divergences in Gut-Restricted Gilliamella and Snodgrassella
Bioengineering, 2022 Gilliamella and Snodgrassella, members of core gut microbiota in corbiculate bees, have high species diversity and adaptability to a wide range of hosts.
Zhengyi Zhang +3 more
doaj +1 more source
ClustAGE: a tool for clustering and distribution analysis of bacterial accessory genomic elements
BMC Bioinformatics, 2018 Background The non-conserved accessory genome of bacteria can be associated with important adaptive characteristics that can contribute to niche specificity or pathogenicity of strains.
Egon A. Ozer
doaj +1 more source
Neutral genomic microevolution of a recently emerged pathogen, salmonella enterica serovar agona [PDF]
, 2013 Salmonella enterica serovar Agona has caused multiple food-borne outbreaks of gastroenteritis since it was first isolated in 1952. We analyzed the genomes of 73 isolates from global sources, comparing five distinct outbreaks with sporadic infections as
Achtman, Mark +9 more
core +3 more sources
Pandora: nucleotide-resolution bacterial pan-genomics with reference graphs
Genome Biology, 2021 We present pandora, a novel pan-genome graph structure and algorithms for identifying variants across the full bacterial pan-genome. As much bacterial adaptability hinges on the accessory genome, methods which analyze SNPs in just the core genome have ...
Rachel M. Colquhoun +10 more
doaj +1 more source
Phylogenomic analysis of lactobacillus curvatus reveals two lineages distinguished by genes for fermenting plant-derived carbohydrates [PDF]
, 2018 Lactobacillus curvatus is a lactic acid bacterium encountered in many different types of fermented food (meat, seafood, vegetables, and cereals). Although this species plays an important role in the preservation of these foods, few attempts have been ...
Chaillou, Stéphane +5 more
core +2 more sources
Genome analysis of a highly virulent serotype 1 strain of streptococcus pneumoniae from West Africa [PDF]
, 2012 Streptococcus pneumoniae is a leading cause of pneumonia, meningitis, and bacteremia, estimated to cause 2 million deaths annually. The majority of pneumococcal mortality occurs in developing countries, with serotype 1 a leading cause in these areas.
Chinelo Ebruke +8 more
core +6 more sources