Results 31 to 40 of about 66,661 (195)
Treatment strategy for insomnia disorder: Japanese expert consensus
PurposeThere is a lack of evidence regarding answers for clinical questions about treating insomnia disorder. This study aimed to answer the following clinical questions: (1) how to use each hypnotic and non-pharmacological treatment differently ...
Yoshikazu Takaesu+24 more
doaj +1 more source
ObjectivesChronic use of benzodiazepines and zolpidem (BDZ/Z-drugs) leads to dependency, cognitive impairment, and falls. Although controlled-release melatonin (Melatonin CR) may be an alternative, a switch in clinical settings has proven difficult.
Ji Hyun An+11 more
doaj +1 more source
Benzodiazepine maintenance for alcohol dependence: A case series
Alcohol addiction is a chronic relapsing syndrome. Benzodiazepines remain as the mainstay for detoxification, taking care of the acute withdrawal syndrome. There is fear of dependence and abuse of benzodiazepines on prolonged use.
Shivanand Kattimani+2 more
doaj +1 more source
Treatment of pediatric convulsive status epilepticus
Status epilepticus is one of the most common life-threatening neurological emergencies in childhood with the highest incidence in the first 5 years of life and high mortality and morbidity rates.
Lena-Luise Becker+11 more
doaj +1 more source
Designer Benzodiazepines: A Review of Toxicology and Public Health Risks
The rising use of designer benzodiazepines (DBZD) is a cat-and-mouse game between organized crime and law enforcement. Non-prohibited benzodiazepines are introduced onto the global drug market and scheduled as rapidly as possible by international ...
Pietro Brunetti+4 more
doaj +1 more source
Aim Chronic insomnia disorder is common and associated with reduced quality of life. Benzodiazepine hypnotics are commonly prescribed for insomnia, but have potential side effects such as concentration impairment, somnolence, and dependence. Lemborexant (
Tomonori Murayama+5 more
doaj +1 more source
Fully Automated Synthesis of Novel TSPO PET Imaging Ligand [18F]Fluoroethyltemazepam
Introduction: Benzodiazepines, including temazepam are described as TSPO antagonists. In fact, TSPO was initially described as a peripheral benzodiazepine receptor (PBR) with a secondary binding site for diazepam.
Dario Fiorenza+5 more
doaj +1 more source
Crystal structure of 1,5-diethyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dithione
In the title compound, C13H16N2S2, the seven-membered ring adopts a boat conformation, with the two phenylene C atoms representing the stern and the methylene C atom as the prow. The thione S atoms and N-bound ethyl groups lie on the opposite side of the
Abderrahman Lamkaddem+5 more
doaj +1 more source
Five traits of personality in benzodiazepine-dependent patients with bipolar disorder
Introduction Benzodiazepines (BZD) are frequently prescribed to patients with bipolar disorder. The use of this medication can become problematic in some cases or even lead to dependence mainly in patients with personality disorders.
N. Charfi+8 more
doaj +1 more source
Benzodiazepines for delirium [PDF]
Delirium occurs in 30% of hospitalised patients and is associated with prolonged hospital stay and increased morbidity and mortality. The results of uncontrolled studies have been unclear, with some suggesting that benzodiazepines may be useful in controlling non-alcohol related delirium.To determine the effectiveness and incidence of adverse effects ...
Almudena Areosa Sastre+2 more
openaire +3 more sources