Biomedicines, 2021 Xanthine oxidoreductase (XOR) is an enzyme that catalyzes the two-step reaction from hypoxanthine to xanthine and from xanthine to uric acid in purine metabolism.
Mai Sekine +2 more
doaj +1 more source
Association between xanthine dehydrogenase tag single nucleotide polymorphisms and essential hypertension. [PDF]
Mol Med Rep, 2015 The present study aimed to investigate the association between xanthine dehydrogenase (XDH) gene polymorphism and essential hypertension in the rural Han Chinese population of Fuxin, Liaoning.
Wu B +11 more
europepmc +2 more sources
Xanthine Oxidase/Dehydrogenase Activity as a Source of Oxidative Stress in Prostate Cancer Tissue
Diagnostics, 2020 Prostate cancer (PC) is one of the most frequent malignancies. Better biomarkers are constantly wanted, such as those which can help with the prediction of cancer behavior. What is also needed is a marker which may serve as a possible therapeutic target.
A. Veljković +7 more
semanticscholar +1 more source
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
XDH and XO Research and Drug Discovery—Personal History
Molecules, 2023 The author will outline the research history of the main issues addressed in this paper. The author has worked on this research himself. XDH, which is responsible for purine degradation, is present in various organisms.
Takeshi Nishino
doaj +1 more source
Pharmacology and clinical drug candidates in redox medicine [PDF]
, 2015 SIGNIFICANCE Oxidative stress is suggested to be a disease mechanism common to a wide range of disorders affecting human health. However, so far, the pharmacotherapeutic exploitation of this, for example, based on chemical scavenging of pro-oxidant ...
Casas, Ana I +11 more
core +3 more sources
Alcool e radicais livres de oxigénio.
Acta Médica Portuguesa, 1993 Oxygen free radicals may be generated during ethanol metabolization by cytochrome P450, or due to the formation of xanthine oxidase by ethanol effect on xanthine dehydrogenase.
M L Mira, C F Manso
doaj +1 more source
GuaB Activity Is Required in Rhizobium tropici During the Early Stages of Nodulation of Determinate Nodules but Is Dispensable for the Sinorhizobium meliloti–Alfalfa Symbiotic Interaction [PDF]
, 2005 The guaB mutant strain Rhizobium tropici CIAT8999-10T is defective in symbiosis with common bean, forming nodules that lack rhizobial content. In order to investigate the timing of the guaB requirement during the nodule formation on the host common ...
Aguilar, Orlando Mario +4 more
core +4 more sources
Determination of Flavin Potential in Proteins by Xanthine/Xanthine Oxidase Method
Bio-Protocol, 2020 This protocol describes a simple xanthine/xanthine oxidase enzymatic equilibration method for determination of the redox potential of a flavin. As an example of the use of this method, we determine the reduction potential of the covalently bound FAD ...
Elena Maklashina, Gary Cecchini
doaj +1 more source
Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress [PDF]
, 2009 Oxidative stress plays an important role in the progression of vascular endothelial dysfunction. The two major systems generating vascular oxidative stress are the NADPH oxidase and the xanthine oxidase pathways. Allopurinol, a xanthine oxidase inhibitor,
George, Jacob, Struthers, Allan D.
core +4 more sources