Results 41 to 50 of about 5,710 (168)
The unusual microtubule polarity in teleost retinal pigment epithelial cells. [PDF]
, 1988 In cells of the teleost retinal pigment epithelium (RPE), melanin granules disperse into the RPE cells long apical projections in response to light onset, and aggregate toward the base of the RPE cell in response to dark onset.
BURNSIDE, Beth, Troutt, L
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European Journal of Neurology, Volume 32, Issue 4, April 2025.ABSTRACT Background and Purpose Early detection of peripheral nerve damage in patients with hereditary transthyretin amyloidosis (ATTRv) has become essential for the prompt initiation of effective, recently approved therapies. In our study, we propose a new variable echo time (vTE) MRI sequence as a non‐invasive method to detect nerve injury in ATTRv ...
Carlo Asteggiano +12 more
wiley +1 more source
Vesicular glutamate release from central axons contributes to myelin damage [PDF]
, 2018 Neuronal activity can lead to vesicular release of glutamate. Here the authors demonstrate that vesicular release of glutamate occurs in axons during ischemic conditions, and that an allosteric modulator of GluN2C/D is protective in models of ischemic ...
A Chamorro +45 more
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Annals of Neurology, Volume 97, Issue 3, Page 425-434, March 2025.Objective In autosomal recessive spastic ataxia of Charlevoix‐Saguenay (ARSACS) disease, severity and age of onset vary greatly, hindering to objectively measure and predict clinical progression. Thickening of the retinal nerve fiber layer is distinctive of ARSACS patients, as assessed by optical coherence tomography, whereas conventional brain ...
Valentina Gigliucci +9 more
wiley +1 more source
Imaging of the Lamina Cribrosa using Swept-Source Optical Coherence Tomography. [PDF]
, 2012 The lamina cribrosa (LC) is the presumed site of axonal injury in glaucoma. Its deformation has been suggested to contribute to optic neuropathy by impeding axoplasmic flow within the optic nerve fibers, leading to apoptosis of retinal ganglion cells. To
Mansouri, Kaweh +2 more
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Alzheimer's &Dementia, Volume 21, Issue 2, February 2025.Abstract INTRODUCTION We previously demonstrated that regulating mitochondria‐associated endoplasmic reticulum (ER) membranes (MAMs) affects axonal Aβ generation in a well‐characterized three‐dimensional (3D) neural Alzheimer's disease (AD) model. MAMs vary in thickness and length, impacting their functions.
Jacob C. Zellmer +6 more
wiley +1 more source
The autonomous axon: a model based on local synthesis of proteins
Biological Research, 2001 In the current understanding of axons, axoplasmic synthesis of proteins is negated, and it is asserted that proteins are transported from perikarya to axons. This 'transport model' in which axons are fully dependent of perikarya is seriously flawed. The '
JAIME ALVAREZ
doaj
Dendritic transport. I. Colchicine stimulates the transport of lysosomal enzymes from cell bodies to dendrites. [PDF]
, 1985 Injection of colchicine into the lateral cerebral ventricle of the rat was found to induce a paradoxical translocation of two lysosomal enzymes, dipeptidyl peptidase II (Dpp II) and acid phosphatase, from the soma of neurons to the dendrites. Following a
Bundman, MC +4 more
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Advanced Science, Volume 12, Issue 3, January 20, 2025.A novel hydrogel‐based transplant system (COCu‐Tac) for induced neural stem cell (iNSCs) therapy in spinal cord injury is introduced. This system offers self‐healing properties, sustained tacrolimus release, and reduces immune rejection without systemic immunosuppression.
Zhenming Tian +8 more
wiley +1 more source
Diffuse axonal injury and oxidative stress: A comprehensive review [PDF]
, 2017 Traumatic brain injury (TBI) is one of the worldâ\u80\u99s leading causes of morbidity and mortality among young individuals. TBI applies powerful rotational and translational forces to the brain parenchyma, which results in a traumatic diffuse axonal ...
Cerretani, Daniela +10 more
core +4 more sources