Results 41 to 50 of about 2,127,716 (198)
Fresh human amniotic membrane effectively promotes the repair of injured common peroneal nerve
Neural Regeneration Research, 2019 Suture and autologous nerve transplantation are the primary therapeutic measures for completely severed nerves. However, imbalances in the microenvironment and adhesion of surrounding tissues can affect the quality of nerve regeneration and repair ...
Zhong-Yuan Zhang +7 more
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Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Optical coherence tomography angiography is a burgeoning imaging modality in Ophthalmology. In this review, we outline the breadth of potential utility for optical coherence tomography angiography for diagnosis and prognostication in neuro‐ophthalmology.
Marzieh Tahmasebi Sarvestani +2 more
wiley +1 more source
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background To evaluate the diagnostic ability of optical coherence tomography (OCT) images to detect posterior pole deformation and anterior displacement of the optic disc (ADOD) in papilledema before and after intracranial pressure reduction with medical treatment.
Gabriel Castilho S. Barbosa +5 more
wiley +1 more source
Journal of Neuroimaging, Volume 35, Issue 3, May/June 2025.ABSTRACT Background and Purpose Fibromyalgia (FM) is a complex condition with unclear pathophysiology. While central sensitization is commonly accepted as the predominant cause of pain symptoms, numerous evidences suggest a role for the peripheral nervous system, particularly small fiber neuropathy.
Benedetta Bianchi +4 more
wiley +1 more source
European Journal of Neurology, Volume 32, Issue 4, April 2025.ABSTRACT Background and Purpose Early detection of peripheral nerve damage in patients with hereditary transthyretin amyloidosis (ATTRv) has become essential for the prompt initiation of effective, recently approved therapies. In our study, we propose a new variable echo time (vTE) MRI sequence as a non‐invasive method to detect nerve injury in ATTRv ...
Carlo Asteggiano +12 more
wiley +1 more source
Annals of Neurology, Volume 97, Issue 3, Page 425-434, March 2025.Objective In autosomal recessive spastic ataxia of Charlevoix‐Saguenay (ARSACS) disease, severity and age of onset vary greatly, hindering to objectively measure and predict clinical progression. Thickening of the retinal nerve fiber layer is distinctive of ARSACS patients, as assessed by optical coherence tomography, whereas conventional brain ...
Valentina Gigliucci +9 more
wiley +1 more source
Alzheimer's &Dementia, Volume 21, Issue 2, February 2025.Abstract INTRODUCTION We previously demonstrated that regulating mitochondria‐associated endoplasmic reticulum (ER) membranes (MAMs) affects axonal Aβ generation in a well‐characterized three‐dimensional (3D) neural Alzheimer's disease (AD) model. MAMs vary in thickness and length, impacting their functions.
Jacob C. Zellmer +6 more
wiley +1 more source
Advanced Science, Volume 12, Issue 3, January 20, 2025.A novel hydrogel‐based transplant system (COCu‐Tac) for induced neural stem cell (iNSCs) therapy in spinal cord injury is introduced. This system offers self‐healing properties, sustained tacrolimus release, and reduces immune rejection without systemic immunosuppression.
Zhenming Tian +8 more
wiley +1 more source
Loss of Smek1 Induces Tauopathy and Triggers Neurodegeneration by Regulating Microtubule Stability
Advanced Science, Volume 11, Issue 40, October 28, 2024.Impairment in microtubule stability and mitochondria transportation is a common pathway in neurodegeneration. The present study elucidates a mechanism by which Smek1 protects against tauopathy by binding to Kif2a in neurons and thereby regulates tau phosphorylation. Smek1 deficiency leads to declined motor and cognition function in mice. Together, they
Ruo‐Nan Duan +11 more
wiley +1 more source
The autonomous axon: a model based on local synthesis of proteins
Biological Research, 2001 In the current understanding of axons, axoplasmic synthesis of proteins is negated, and it is asserted that proteins are transported from perikarya to axons. This 'transport model' in which axons are fully dependent of perikarya is seriously flawed. The '
JAIME ALVAREZ
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