Rhamnose-Containing Compounds: Biosynthesis and Applications
Rhamnose-associated molecules are attracting attention because they are present in bacteria but not mammals, making them potentially useful as antibacterial agents. Additionally, they are also valuable for tumor immunotherapy.
Siqiang Li+6 more
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Isolation of Endogenous Activator of Glucuronide Formation in Liver [PDF]
A purified compound of the activator of glucuronide formation was isolated from a boiled extract of rat liver by charcoal adsorption, ethanol fractionation of barium salts, and finally paper and Dowex-l column chromatographies.
Taketa, Kazuhisa
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In Bacillus subtilis, Listeria monocytogenes and in two Mycobacteria, it was previously shown that yvcK is a gene required for normal cell shape, for optimal carbon source utilization and for virulence of pathogenic bacteria.
Elodie Foulquier, Anne Galinier
doaj +1 more source
Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency, which may manifest as neonatal hyperbilirubinemia, is the most prevalent erythrocytic enzyme-related disease in the world.
Jia-Xin Xu+8 more
doaj +1 more source
Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells [PDF]
Undifferentiated and differentiated HL-60 leukemic cells possess nucleotide receptors which functionally couple to phospholipase C via pertussis toxin-sensitive guanine nucleotide-binding proteins (G-proteins).
Seifert, Roland+1 more
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Expression and purification of functional human glycogen synthase-1:glycogenin-1 complex in insect cells [PDF]
We report the successful expression and purification of functional human muscle glycogen synthase (GYS1) in complex with human glycogenin-1 (GN1). Stoichiometric GYS1:GN1 complex was produced by co-expression of GYS1 and GN1 using a bicistronic pFastBac™-
Hunter, Roger W.+4 more
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Scalable multi-enzyme platforms for the in vitro glycoengineering of therapeutic proteins & synthesis of human milk oligosaccharides [PDF]
Sugars in their free form or conjugated to biomolecules like proteins, lipids, and small molecules have significant functional roles in different biological processes.
Mahour, R.
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Identification of a carbohydrate recognition motif of purinergic receptors
As a major class of biomolecules, carbohydrates play indispensable roles in various biological processes. However, it remains largely unknown how carbohydrates directly modulate important drug targets, such as G-protein coupled receptors (GPCRs).
Lifen Zhao+7 more
doaj +1 more source
De novo pyrimidine nucleotide biosynthesis in isolated rat glomeruli [PDF]
De novo pyrimidine nucleotide biosynthesis in isolated rat glomeruli. Uracil ribonucleotide–sugars and aminosugars are required for glomerular basement membrane (GBM) biosynthesis.
Cortes, Pedro+2 more
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Sterol 3β-glucosyltransferase biocatalysts with a range of selectivities, including selectivity for testosterone [PDF]
The main objectives of this work were to characterise a range of purified recombinant sterol 3β-glucosyltransferases and show that rational sampling of the diversity that exists within sterol 3β-glucosyltransferase sequence space can result in a range of
Altschul+30 more
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