Results 1 to 10 of about 135,006 (287)

Platelet antibody detection assays: a single-laboratory comparison of MAIPA, PIFT, and microsphere-based multiplex assays Pak-Lx [PDF]

Hematology, Transfusion and Cell Therapy
Background and Objectives: The identification of platelet antibodies is essential for diagnosing and managing conditions such as fetal and neonatal alloimmune thrombocytopenic purpura, post-transfusion purpura, and immune platelet refractoriness ...
Thiago Henrique Costa, Carolina Bonet-Bub, José Mauro Kutner   +2 more
doaj   +2 more sources

Allele and haplotype frequencies of human platelet and leukocyte antigens in platelet donors [PDF]

Einstein (São Paulo), 2019
Objective To described the allele and haplotype frequencies of human leukocyte antigen genes at the -A, -B loci and human platelet antigen genes for human platelet antigen systems 1 to 9, 11 and 15 in blood.
Valeria de Freitas Dutra, Carolina Bonet Bub, Thiago Henrique Costa, Leandro Dinalli Santos, Eduardo Peres Bastos, Maria Giselda Aravechia, José Mauro Kutner   +6 more
doaj   +5 more sources

Association of the human platelet antigens polymorphisms with platelet count in patients with COVID-19

Frontiers in Medicine, 2023
Polymorphism in human platelet antigen (HPA)-1 and HPA-3 (GPIIb/IIIa), HPA-2 (GPIb/IX), HPA-4 (GPIIIa), HPA-5 (GPIa/IIa), & HPA-15 (CD109) was investigated in 86 COVID-19-infected patients with thrombocytopenia (Group A) and 136 COVID-19-infected ...
Kazem Ghaffari, Kazem Ghaffari, Mahsa Ashrafi Rad, Amin Moradi Hasan-Abad, Mersedeh Khosravi, Arefeh Benvidi, Mahsa Iraji, Heidar Ali Heidari Khargh, Ali Ghasemi, Ali Ghasemi   +9 more
doaj   +3 more sources

Human platelet antigens and primary immune thrombocytopenia

Revista Brasileira de Hematologia e Hemoterapia, 2017
Vagner Castro
doaj   +4 more sources

Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets

Haematologica, 2022
Approximately 20% of patients receiving multiple platelet transfusions develop platelet alloantibodies, which can be directed against human leukocyte antigens (HLA) and, to a lesser extent, against human platelet antigens (HPA).
Thijs L.J. van Osch, Janita J. Oosterhoff, Arthur E. H. Bentlage, Jan Nouta, Carolien A. M. Koeleman, Dionne M. Geerdes, Juk Yee Mok, Sebastiaan Heidt, Arend Mulder, Wim J. E. van Esch, Rick Kapur, Leendert Porcelijn, C. Ellen van der Schoot, Masja de Haas, Manfred Wuhrer, Jan Voorberg, Gestur Vidarsson   +16 more
doaj   +1 more source

Human platelet antigens – 2013 [PDF]

Vox Sanguinis, 2013
To date, 33 human platelet alloantigens (HPAs) have been identified on six functionally important platelet glycoprotein (GP) complexes and have been implicated in alloimmune platelet disorders including foetal and neonatal alloimmune thrombocytopenia (FNAIT), posttransfusion purpura (PTP) and multitransfusion platelet refractoriness (MPR). The greatest
Brian R. Curtis, Janice G. McFarland
openaire   +3 more sources

Genotyping of Human Platelet Antigen-1 to -5 and -15 by Polymerase Chain Reaction with Sequence-specific Primers (PCR-SSP) and Real-time PCR in Azeri Blood Donors

Iranian Journal of Allergy, Asthma and Immunology, 2021
Human platelet antigens (HPAs) are glycoproteins on the platelet surface that a single nucleotide mutation in the coding region gene could lead to the variation of different HPA polymorphisms. These antigens have shown variation among different races and
Seyed Ghader Azizi, Shahram Samiee, Mojgan Shaiegan, Maryam Zadsar   +3 more
doaj   +1 more source

The origin of ABH antigens on human platelets [PDF]

Blood, 1985
Abstract ABH antigens are present on platelets from individuals of the corresponding red cell phenotype, but the extent to which these antigens are intrinsic or adsorbed remains undefined. To evaluate platelets for intrinsic H substance, an IgM mouse monoclonal antibody against type 2H chain (the intrinsic H structure found on ...
Wendell F. Rosse, Robert A. Dunstan, Marcus B. Simpson, Robert W. Knowles   +3 more
openaire   +4 more sources

Simultaneous genotyping for human platelet antigen systems and HLA-A and HLA-B loci by targeted next-generation sequencing

Frontiers in Immunology, 2022
In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang, Jielin Wang, Xuan You, Xuan You, Yanmin He, Yanmin He, Xiaozhen Hong, Xiaozhen Hong, Ji He, Ji He, Sudan Tao, Sudan Tao, Faming Zhu, Faming Zhu   +13 more
doaj   +1 more source

Determination of platelet antigens and glycoproteins in the human fetus [PDF]

Blood, 1986
The autosomal recessive transmission of Glanzmann's thrombasthenia (GT) and Bernard-Soulier syndrome (BSS), together with requests of families who already had children with these diseases, prompted us to investigate the feasibility of their antenatal diagnosis. The preliminary step leading to the early detection of GT or BSS was to characterize, in the
Bernadette Boizard, Fernand Daffos, Jean Luc Wautier, Yves Gruel, François Forestier, Jacques P. Caen   +5 more
openaire   +3 more sources