Results 1 to 10 of about 1,857,199 (369)

Precise solid-phase synthesis of CoFe@FeO_x nanoparticles for efficient polysulfide regulation in lithium/sodium-sulfur batteries. [PDF]

Nat Commun, 2023
Complex metal nanoparticles distributed uniformly on supports demonstrate distinctive physicochemical properties and thus attract a wide attention for applications.
Chen Y, Yao Y, Zhao W, Wang L, Li H, Zhang J, Wang B, Jia Y, Zhang R, Yu Y, Liu J.   +10 more
europepmc   +2 more sources

Laser solid-phase synthesis of single-atom catalysts

Light: Science & Applications, 2021
Synthesis of Pt single atom catalysts is achieved by one-step laser irradiation of “isolated” H2PtCl6 precursor on graphene oxide, via filtration and freeze-drying sublimation, by simultaneous pyrolysis of the precursor and reduction of graphene oxide.
Yudong Peng, Jianyun Cao, Yang Sha, Wenji Yang, Lin Li, Zhu Liu   +5 more
doaj   +2 more sources

Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles

Molecules, 2013
Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior.
Shelli R. McAlpine, Seong Jong Kim
doaj   +2 more sources

The Facile Solid-Phase Synthesis of Thiazolo-Pyrimidinone Derivatives [PDF]

Molecules
A thiazolo-pyrimidinone derivative library was developed through a facile solid-phase synthesis method. For the reaction, the thiazolo[4,5-d]pyrimidin-7(6H)-one structure was synthesized through efficient Thorpe–Ziegler and cyclization reactions.
Shuanghui Hua, Jimin Moon, Taeho Lee
doaj   +2 more sources

Dielectrophoretic bead-droplet reactor for solid-phase synthesis [PDF]

Nature Communications
Solid-phase synthesis underpins many advances in synthetic and combinatorial chemistry, biology, and material science. The immobilization of a reacting species on the solid support makes interfacing of reagents an important challenge in this approach. In
Punnag Padhy, Mohammad Asif Zaman, Michael Anthony Jensen, Yao-Te Cheng, Yogi Huang, Mo Wu, Ludwig Galambos, Ronald Wayne Davis, Lambertus Hesselink   +8 more
doaj   +2 more sources

Development of Rapid and Facile Solid-Phase Synthesis of PROTACs via a Variety of Binding Styles. [PDF]

ChemistryOpen, 2022
Xu H, Kurohara T, Takano R, Yokoo H, Shibata N, Ohoka N, Inoue T, Naito M, Demizu Y.   +8 more
europepmc   +2 more sources

Automated synthesis of prexasertib and derivatives enabled by continuous-flow solid-phase synthesis

Nature Chemistry, 2021
Recent advances in end-to-end continuous-flow synthesis are rapidly expanding the capabilities of automated customized syntheses of small-molecule pharmacophores, resulting in considerable industrial and societal impacts; however, many hurdles persist ...
Chenguang Liu, Jiaxun Xie, Wenbin Wu, Mu Wang, Weihao Chen, Shabana Binte Idres, Jiawei Rong, L. Deng, Saif A. Khan, Jie Wu   +9 more
semanticscholar   +1 more source

Heterocycles as a Peptidomimetic Scaffold: Solid-Phase Synthesis Strategies

Pharmaceuticals, 2021
Peptidomimetics are a privileged class of pharmacophores that exhibit improved physicochemical and biological properties. Solid-phase synthesis is a powerful tool for gaining rapid access to libraries of molecules from small molecules to biopolymers and ...
Aizhan Abdildinova, Mark J. Kurth, Young-Dae Gong   +2 more
doaj   +1 more source

Solid‐Phase Synthesis of Lipidated Peptides [PDF]

Chemistry – A European Journal, 2005
AbstractA new flexible and efficient methodology for the solid‐phase synthesis of lipidated peptides has been developed. The approach is based on the use of previously synthesized building blocks and overcomes the limitations of previously reported methods, since long doubly lipidated peptides can be synthesized by using this route. Furthermore, it was
Lumbierres, M., Palomo, J., Kragol, G., Roehrs, S., Müller, O., Waldmann, H.   +5 more
openaire   +9 more sources

Efficient Syntheses of 1,2,3-Triazoloamide Derivatives Using Solid- and Solution-Phase Synthetic Approaches

Molecules, 2015
Efficient synthetic routes for the preparation of secondary and tertiary 1,2,3-triazoloamide derivatives were developed. A secondary α-1,2,3-triazoloamide library was constructed and expanded by a previously developed solid-phase synthetic route and a ...
Doohyun Lee, Daehun Kim, Seungyeon Lee, Taegeum Kim, Joobin Kim, Sohee Kim, Kwang-Hyeon Liu, Sangkyu Lee, Jong-Sup Bae, Kyung-Sik Song, Chang-Woo Cho, Youn Kyung Son, Dong Jae Baek, Taeho Lee   +13 more
doaj   +1 more source