Results 101 to 110 of about 2,347 (126)

Antifungal and anti‐biofilm effects of 6‐shogaol againstCandida auris

Journal of Applied Microbiology, 2020
This study aimed to assess the antifungal and anti-biofilm effects of 6-shogaol against Candida auris using in vitro phenotypic and genotypic analyses.Our results showed that 6-shogaol exhibited antifungal as well as anti-biofilm activity by inhibiting biofilm formation and eradicating the preformed biofilms of C. auris.
H.‐R. Kim, Y.‐B. Eom
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Pharmacokinetics of [6]-shogaol, a pungent ingredient of Zingiber officinale Roscoe (Part I)

Journal of Natural Medicines, 2010
To investigate the pharmacokinetics of [6]-shogaol, a pungent ingredient of Zingiber officinale Roscoe, the pharmacokinetic parameters were determined by using (14)C-[6]-shogaol (labeled compound) and [6]-shogaol (non-labeled compound). When the labeled compound was orally administered to rats, the maximum plasma concentration (C (max)) and the area ...
Akitoshi, Asami, Tsutomu, Shimada, Yasuharu, Mizuhara, Takayuki, Asano, Shuichi, Takeda, Takashi, Aburada, Ken-Ichi, Miyamoto, Masaki, Aburada   +7 more
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Synthesis, evaluation, and metabolism of novel [6]-shogaol derivatives as potent Nrf2 activators

Free Radical Biology and Medicine, 2016
Oxidative stress is a central component of many chronic diseases. The Kelch-like ECH-associated protein 1 (Keap1)-nuclear factor erythroid 2 p45-related factor 2 (Nrf2) system is a major regulatory pathway of cytoprotective genes against oxidative and electrophilic stress.
Yingdong, Zhu, Pei, Wang, Yantao, Zhao, Chun, Yang, Anderson, Clark, TinChung, Leung, Xiaoxin, Chen, Shengmin, Sang   +7 more
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Formation of 6-Shogaol of Ginger Oil Under Different Drying Conditions

Drying Technology, 2011
Ginger (Zingiber officinalis, Roscoe) is a common ingredient in various foods and beverages. It contains potent anti-inflammatory agents and oleoresin, in which 6-gingerol and 6-shogaol are major active compounds. Studies show that 6-shogaol has stronger anti-inflammatory effects.
Tzou-Chi Huang, Chao-Chin Chung, Han-Yang Wang, Chung-Lim Law, Ho-Hsien Chen   +4 more
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From Kitchen Spice to Neuroprotector: The Role of 6-Shogaol in Parkinson’s Disease Management

Journal of Agricultural and Food Chemistry
6-Shogaol (6S), the major bioactive component of ginger, exhibits diverse pharmacological properties. This study investigated the therapeutic potential of 6S against α-synuclein (α-Syn), a key pathological marker in Parkinson's disease (PD), using an in vivo methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD mouse model and an in vitro ...
Jiahui Jin, Xiran Li, Yunxi Wang, Zishu Yan, Anran Lv, Yanjun Zhang, Pengwei Zhuang, Hong Guo   +7 more
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Integrated network pharmacology and cellular assay for the investigation of an anti-obesity effect of 6-shogaol

Food Chemistry, 2022
Bimal Chitrakar, Xianghong Wang, Yaxin Sang   +2 more
exaly  

Role of 6-Shogaol Against Ovarian Torsion Detorsion-InducedReproductive Organ Damage

2020
6-Shogaol was examined on ovarian torsion detorsion (T/D) rat model to find out the potential beneficial results exist or not. 4 groups were composed to establish the experimental step. Sprague-Dawley female rats were used in the experiment. Each group included 8 rats and 32 rats were examined totally.
GÜLER, Mustafa Can, TANYELİ, Ayhan, ERASLAN, Ersen, EKİNCİ AKDEMİR, Fazile Nur   +3 more
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6-Shogaol inhibits the proliferation, apoptosis, and migration of rheumatoid arthritis fibroblast-like synoviocytes via the PI3K/AKT/NF-κB pathway

Phytomedicine, 2023
Jia-Xu Chen, Zhaohui Gong, Dongmei Pan
exaly  

Antifungal and anti-biofilm effects of 6-shogaol against Candida auris

Journal of Applied Microbiology, 2021
Yong-Bin Eom
exaly  

Re-examination of 6-shogaol biotransformation byAspergillus niger

Archives of Pharmacal Research, 1995
openaire   +1 more source