Results 91 to 100 of about 150,764 (232)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Équivalence terminologique en linguistique : une analyse de certaines disparités entre le russe et le français

Langues & Cultures
Cet article aborde les défis liés à l’établissement des équivalences terminologiques entre le russe et le français dans le domaine de la linguistique. Il met en lumière la manière dont les variations terminologiques sont amplifiées par les divergences ...
Denis ZOLOTUKHIN
doaj  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Bequests and the Intergenerational Degree of Altruism [PDF]

We consider an OLG model with production and altruistic agents initially developed by Barro (1974). Through a simple example, we show that, contrary to the intuition of Abel (1987) and Weil (1987), an increase in the degree of altruism can result in a ...
Emmanuel THIBAULT
core  

PROBLEMES DE MODULES FORMELS [d’après Drinfeld, Kontsevich, Hinich, Manetti, Pridham, Lurie ...] [PDF]

, 2016
International audienceTexte sur l'exposé Bourbaki du 16 Janvier ...
Toën, Bertrand
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Identité, évolution et discernabilité des objets dans les systèmes d'information et les bases de données

, 2012
The principles and procedures for managing technical data changes specifically addressed by Product Lifecycle Management systems are examined in the context of fast changing and serially produced technical objects.
Giacomoni, Gilbert, Sardas, Jean-Claude
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Complémentarité ou équivalence des matériaux naturels et synthétiques pour l'étanchéité d'ouvrages de stockage des déchets ?

Sciences, Eaux & Territoires, 2001
La réglementation française relative au stockage des déchets ménagers définit les matériaux à mettre en oeuvre pour assurer l'étanchéité des casiers de centres de stockage.
S. LAMBERT
doaj  

$f$-Asymptotically $\mathcal{I}_{\sigma\theta}$-Equivalence of Real Sequences

Journal of Mathematical Sciences and Modelling, 2020
In this manuscript, we present the ideas of asymptotically $[{\mathcal{I}_{\sigma\theta}}]$-equivalence, asymptotically ${\mathcal{I}_{\sigma\theta}}(f)$-equivalence, asymptotically $[{\mathcal{I}_{\sigma\theta}}(f)]$-equivalence and asymptotically ...
Erdinç Dundar, Nimet Akın
doaj