Results 71 to 80 of about 150,764 (232)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Tourisme, santé et bien-être : analyse en phraséologie contrastive de quelques expressions du français et de l'italien [PDF]

open access: yes, 2010
International audienceIn this paper, we proceed to a contrastive phraseological analysis of some compound nouns containing the French word tourisme or its Italian equivalent turismo and dealing with health and wellness.
Cetro, Rosa
core   +2 more sources

Le paiement par conversion des redevances seigneuriales dans un village franconien au XVe siècle

open access: yes, 2009
Étude statistique de l'écart entre prélèvement seigneurial stipulé et formes effectives du versement par les tenanciers, dans la comptabilité de l'Hôpital du St-Esprit de Nuremberg entre1396 et ...
Demade, Julien
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Equivalence – Equivalence Relations: Effects of Training-Structure and Competition Between Arbitrary and Relations of Physical Similarity

open access: yesRevista Argentina de Ciencias del Comportamiento, 2011
In this paper we study the necessary and sufficient conditions for the training of conditional relations, the formation of equivalence classes and relations of "equivalence - equivalence".
Primero, Gerardo   +6 more
doaj  

Equivalence in Bilingual Lexicography: Criticism and Suggestions*

open access: yesLexikos, 2011
<p>Abstract: A reminder of general problems in the formation of terminology, as illustrated by theGerman Äquivalence (Eng. equivalence) and äquivalent (Eng.
Herbert Ernst Wiegand
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

TRADUIRE LES CONTRATS DU DROIT FRANÇAIS PAR ÉQUIVALENCE FONCTIONNELLE/TRANSLATING FRENCH LAW CONTRACTS THROUGH FUNCTIONAL EQUIVALENCE/TRADUCEREA CONTRACTELOR DIN DREPTUL FRANCEZ PRIN INTERMEDIUL ECHIVALENȚEI FUNCȚIONALE [PDF]

open access: yesStudii si Cercetari Filologice: Seria Limbi Straine Aplicate, 2020
The topic of this paper is represented by the translation of French contracts through functional equivalence. In the first part of the study, we present the avatars of the concept of equivalence in Translation Studies, the notion of dynamic equivalence
Carmen-Ecaterina Ciobâcă   +1 more
doaj  

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