Results 71 to 80 of about 137,191 (197)

Gauge equivalence problem on differential operators under fiber-preserving transformation [PDF]

open access: yesJournal of Mahani Mathematical Research
This paper focuses on investigating the equivalence problem for fifth-order differential operators (FODOs) on the line under general fiber-preserving transformations.
Morteza Bakhshandeh   +2 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Äquivalenz, Vergleichbarkeit und Übersetzbarkeit

open access: yesTraduction et Langues, 2009
Cet article traite des questions relatives à la comparabilité, l'équivalence et la traduisibilité. En fait, la comparabilité est bien comprise dans un cadre de linguistique contrastive.
Djamel Eddine Lachachi
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Équivalence terminologique en linguistique : une analyse de certaines disparités entre le russe et le français

open access: yesLangues & Cultures
Cet article aborde les défis liés à l’établissement des équivalences terminologiques entre le russe et le français dans le domaine de la linguistique. Il met en lumière la manière dont les variations terminologiques sont amplifiées par les divergences ...
Denis ZOLOTUKHIN
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Equivalence – Equivalence Relations: Effects of Training-Structure and Competition Between Arbitrary and Relations of Physical Similarity

open access: yesRevista Argentina de Ciencias del Comportamiento, 2011
In this paper we study the necessary and sufficient conditions for the training of conditional relations, the formation of equivalence classes and relations of "equivalence - equivalence".
Primero, Gerardo   +6 more
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

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