Results 61 to 70 of about 1,270,842 (242)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
A simple approach to distributed objects in prolog
, 2002 We present the design of a distributed object system for Prolog, based on adding remote execution and distribution capabilities to a previously existing object system. Remote execution brings RPC into a Prolog system, and its semantics is easy to express
Carro Liñares, Manuel +1 more
core
Effects of non-unity Lewis numbers in diffusion Flames [PDF]
, 1994 The purpose of this work is to carry out direct numerícal simulations of diffusion controlled combustión with non-unity Lewis numbers for the reactants and producís, thus accounting for the düferential diífusion effects of the temperature and ...
Higuera Antón, Francisco +3 more
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Pós: Revista do Programa de Pós-Graduação em Arquitetura e Urbanismo da FAUUSP, 2021 Parto de um artigo de Nelson Maldonado-Torres, no qual ele apresenta dez teses com vistas a uma analítica da colonialidade e da decolonialidade, mas ressalvo sua pouca atenção concedida à análise espacial, como faz boa parte da literatura decolonial ...
LEONARDO NAME
doaj
Comunicar en inglés: un aprendizaje lingüístico a través de un aprendizaje social [PDF]
, 1987 El desarrollo de la competencia comunicativa en una lengua añadida no es exclusivamente un aprendizaje lingüístico sino que se trata, también, de un aprendizaje social.
Vez Jeremías, José Manuel
core
Analyzing logic programs with dynamic scheduling [PDF]
, 1994 Traditional logic programming languages, such as Prolog, use a fixed left-to-right atom scheduling rule. Recent logic programming languages, however, usually provide more flexible scheduling in which computation generally proceeds leftto- right but in ...
García de la Banda, M. +2 more
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Archivos Latinoamericanos de NutriciónRESUMEN Las raíces y tubérculos tropicales (RTT) son alimentos básicos de la dieta de los pobladores de estas zonas; son producidos por pequeños y medianos agricultores y se les ha prestado poca atención.
Adriana Blanco-Metzler +2 more
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