Results 101 to 110 of about 682,713 (259)

Transamination of α-keto acids catalyzed by pyridoxals

open access: yes上海师范大学学报. 自然科学版, 2016
In this paper,we designed and synthesized a series of pyridoxals tagged with different functional groups.The pyridoxals exhibited high catalytic activity in transamination of α-keto acids to obtain various amino acids in good yields.This transamination ...
CHEN Jing, ZHAO Junyu, ZHAO Baoguo
doaj   +1 more source

Supercritical carbon dioxide hops extracts with antimicrobial properties [PDF]

open access: yes, 2015
Extracts obtained from hops (Humulus lupulus L., Cannabaceae) by supercritical fluid extraction (SFE), SFE followed by isomerization, as well as by conventional technique, were investigated for their chemical composition and antibacterial activity ...
Arsić, Ivana   +6 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Synthesis of new Cα-tetrasubstituted α-amino acids

open access: yesBeilstein Journal of Organic Chemistry, 2009
Cα-Tetrasubstituted α-amino acids are important building blocks for the synthesis of peptidemimetics with stabilized secondary structure, because of their ability to rigidify the peptide backbone.
Andreas A. Grauer, Burkhard König
doaj   +1 more source

Fatty acids composition of fruits of selected Central European sedges (Carex L. Cyperaceae)

open access: yesGrasas y Aceites, 2010
Fatty acids in the fruits of 13 sedge species (Carex L., Cyperaceae) were analyzed. The oil contents in the fruits of the studied sedges ranged from 3.73 and 46.52%. In the studied fruit oils 14 different fatty acids were identified. The main unsaturated
Anna Bogucka-Kocka, Magdalena Janyszek
doaj   +1 more source

IMPROVING THE HOP UTILIZATION IN THE BEER BIOTECHNOLOGY [PDF]

open access: yes, 2008
The rate of isomerization of alpha acids to iso-alpha acids (the bittering compounds in beer) was characterized over a representative pH, wort concentration, time boiling and temperature range during the boiling portion of the brewing process. Because of
Goina, Veronica   +4 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Protometabolic Reduction of NAD+ with α‑Keto Acids

open access: yesJACS Au, 2021
Shibaji Basak   +2 more
doaj   +1 more source

Systems chemistry of α-amino acids and peptides

open access: yesBIO Web of Conferences, 2014
Pathways have been disclosed in the past decade, which support the possibility that α-amino acids could have contributed to self-organization processes leading to the emergence of life.
Danger Grégoire   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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