Results 81 to 90 of about 2,396,283 (252)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Ability of phenolic acids to protect α-tocopherol

Czech Journal of Food Sciences, 2010
The ability of phenolic acids (gallic, gentisic, protocatechuic, syringic, vanillic, ferulic, caffeic, and sinapic; 600 mg/kg) to protect α-tocopherol was tested during the heating of sunflower oil on a hot plate set at 180°C and was compared with the ...
Zuzana Réblová, Petra Okrouhlá
doaj   +1 more source

Organocatalytic Michael addition–lactonisation of carboxylic acids using α,β-unsaturated trichloromethyl ketones as α,β-unsaturated ester equivalents [PDF]

, 2014
The authors thank the Royal Society for a University Research Fellowship (ADS), The Carnegie Trust for the Universities of Scotland (LCM), Syngenta/EPSRC (Case award to DGS), GSK/EPSRC (CASE award to SRS), the EU (IEF for CS), and the European Research ...
Morrill, L.C., D'Hollander, A.C.A., O'Riordan, Timothy J. C., O'Riordan, T.J.C., Taylor, James E., Shapland, Peter, Smith, S.R., Morrill, Louis, Shapland, P., Stark, Daniel G., Smith, Siobhan R., Simal Fernandez, Carmen, D'Hollander, Agathe C. A., Stark, D.G., Smith, A.D., Taylor, J.E., Squires, James A., Squires, J.A., Smith, Andrew D., Simal, Carmen   +19 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

HPLC Determination of α-keto Acids in Human Serum and Urine after Derivatization with 4-Nitro-1,2-phenylenediamine [PDF]

Pakistan Journal of Analytical & Environmental Chemistry, 2013
The determination of α-keto acids has clinical importance, because these are intermediates in a number of biochemical processes. This work reports the development of an HPLC procedure for the analysis α-keto acids in blood and urine samples after ...
Shamroz Bano Sahito, Abdul Hameed Channer, Gulam Murtaza Mastoi, Muhammad Yar Khuhawar, Khalida Parveen Mahar, Kulsoom Ubedullah Abbasi, Abdul Jabbar Kandhro   +6 more
doaj  

Transamination of α-keto acids catalyzed by pyridoxals

上海师范大学学报. 自然科学版, 2016
In this paper,we designed and synthesized a series of pyridoxals tagged with different functional groups.The pyridoxals exhibited high catalytic activity in transamination of α-keto acids to obtain various amino acids in good yields.This transamination ...
CHEN Jing, ZHAO Junyu, ZHAO Baoguo
doaj   +1 more source

Lactone Carboxylic Acids. II. Synthesis of α-Benzylideneparaconic Acids [PDF]

, 1967
The reaction of ethyl γ,γ-dialkylparaconate with aromatic aldehydes, i.e., benzaldehyde, anisaldehyde, p-chlorobenzaldehyde, and piperonal, has been investigated. The condensation took place at the α-position of the lactone ring. As the acidic components,
Torii, Sigeru, Nagae, Hiroyuki, Takeda, Akira   +2 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Synthesis of new Cα-tetrasubstituted α-amino acids

Beilstein Journal of Organic Chemistry, 2009
Cα-Tetrasubstituted α-amino acids are important building blocks for the synthesis of peptidemimetics with stabilized secondary structure, because of their ability to rigidify the peptide backbone.
Andreas A. Grauer, Burkhard König
doaj   +1 more source

Fatty acids composition of fruits of selected Central European sedges (Carex L. Cyperaceae)

Grasas y Aceites, 2010
Fatty acids in the fruits of 13 sedge species (Carex L., Cyperaceae) were analyzed. The oil contents in the fruits of the studied sedges ranged from 3.73 and 46.52%. In the studied fruit oils 14 different fatty acids were identified. The main unsaturated
Anna Bogucka-Kocka, Magdalena Janyszek
doaj   +1 more source