Results 241 to 250 of about 57,508 (269)

Impact of a multicarbohydrase containing α-galactosidase and xylanase on ileal digestible energy, crude protein digestibility, and ileal amino acid digestibility in broiler chickens

, 2018
A. Jasek, R.E. Latham, Alfredo Mañón, S. Llamas Moya, Roshan Babu Adhikari, R. Poureslami, J.T. Lee   +6 more
openalex   +1 more source

Circulating Metabolites Treat Human TMJ‐OA by Eliminating Senescent Chondrocytes via the C1QBP/C1q/p14ARF Axis

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
ABSTRACT Temporomandibular joint osteoarthritis (TMJ‐OA) is a progressive degenerative disorder, for which therapeutic interventions remain limited. The disruption of metabolic homeostasis plays a critical role in the pathogenesis and advancement of TMJ‐OA.
Bowen Meng, Xin Li, Benyi Yang, Yan Qu, Yifan He, Chaoran Fu, Zhe An, Antong Wu, Yuzhuo Hei, Rong Zhang, Wenyi Cai, Lingyunbo Kong, Rui Li, Meng Hao, Zeyuan Cao, Xueli Mao, Janak Lal Pathak, Yang Cao, Songtao Shi, Qingbin Zhang   +19 more
wiley   +1 more source

Multi‐environment evaluation of raffinose‐family oligosaccharide content in diverse dry bean varieties and their reduction upon canning

Journal of the Science of Food and Agriculture, Volume 106, Issue 3, Page 1904-1913, February 2026.
Abstract BACKGROUND The substantial amount of raffinose family oligosaccharide (RFO) in dry beans causes flatulence and digestive discomfort, limiting the appeal of dry bean food products. Substantial variation exists in RFO content among dry bean varieties, and various food processing steps such as soaking and canning are known to reduce RFO levels ...
Brendan M. O'Leary, Vinti Kumari, Todd Reid, Parthiba Balasubramanian   +3 more
wiley   +1 more source

Dissociation of globotriaosylceramide and impaired endothelial function in α-galactosidase-A deficient EA.hy926 cells. [PDF]

Mol Genet Metab, 2018
Kaissarian N, Kang J, Shu L, Ferraz MJ, Aerts JM, Shayman JA.   +5 more
europepmc   +1 more source

Activity-based metaproteomics driven discovery and enzymological characterization of potential α-galactosidases in the mouse gut microbiome

Jianbing Jiang, Diana Czuchry, Yan-Xia Ru, Huipai Peng, Junfeng Shen, Teng Wang, Wenjuan Zhao, Wei‐Hua Chen, Sen‐Fang Sui, Yaowang Li, Nan Li   +10 more
openalex   +1 more source

Lipid Nanoparticles Delivering ClpP‐mRNA Suppress Pyroptosis and Senescence in Intervertebral Disc Degeneration via mTOR/BNIP3‐Activated Mitophagy

Rare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang, Zhiqiang Wang, Tong Zhang, Shicheng Qiu, Guang Yang, Yanzheng Gao, Xiaofeng Lian, Xin Peng   +7 more
wiley   +1 more source

α-galactosidase A deficiency promotes von Willebrand factor secretion in models of Fabry disease. [PDF]

Kidney Int, 2019
Kang JJ, Kaissarian NM, Desch KC, Kelly RJ, Shu L, Bodary PF, Shayman JA.   +6 more
europepmc   +1 more source

β-Galactosidase and α-L-Arabinofuranosidase Activities and Gene Expression in European and Chinese Pear Fruit During Ripening

, 2007
Mercy Mwaniki, Francis M. Mathooko, Kyoko Hiwasa, Akira Tateishi, Naoki Yokotani, Koichiro Ushijima, Ryohei Nakano, Akitsugu Inaba, Yasutaka Kubo   +8 more
openalex   +2 more sources

Proteomic Profiling of Alveolar Macrophages Identifies Loss of Lysosomal Content as an Indicator of Nanofiber‐Induced Frustrated Phagocytosis

Small, Volume 22, Issue 11, 20 February 2026.
This proteomic study examines how nanofibers affect lung macrophages by analyzing protein changes following exposure to various fibrous materials. Nanofibers triggered the release of inflammatory enzymes, and importantly, lysosomal content release was identified as an early event associated with frustrated phagocytosis. Seventeen sensitive and relevant
Tobias Stobernack, Antje Vennemann, Carla Ribalta, Julia Schendel, Oliver Gräb, Rico Ledwith, Mario Pink, Andrea Haase, Martin Wiemann, Verónica I. Dumit   +9 more
wiley   +1 more source

Fluorophore Modulates Intracellular Distribution of Enzyme‐Instructed Self‐Assembly of Short Peptides in Osteosarcoma Cells

Small Methods, Volume 10, Issue 3, 9 February 2026.
Fluorophores at the peptide C‐terminus reprogram EISA behavior in osteosarcoma cellsshifting ER vs mitochondrial targeting, altering assembly, and tuning cytotoxicity. Abstract Enzyme‐instructed self‐assembly (EISA) of peptides offers a versatile strategy for developing intracellular nanomedicines, yet the role of C‐terminus fluorophores in modulating ...
Yali Huang, Meihui Yi, Yuchen Qiao, Bing Xu   +3 more
wiley   +1 more source