Results 251 to 260 of about 57,508 (269)
Characterization of a highly stable α-galactosidase from thermophilic Rasamsonia emersonii heterologously expressed in a modified Pichia pastoris expression system. [PDF]
An JL, Zhang WX, Wu WP, Chen GJ, Liu WF.
europepmc +1 more source
This review presents aggregation (AIE)‐induced emission materials as an integrated platform that links cancer care and fertility preservation. They detect tumors, guide surgery, and enable light‐activated therapy while monitoring reproductive health. Bright and stable signals support early diagnosis and navigation.
Yaoqin Mu, Yanbo Li, Jun Dai, Kezhen Li
wiley +1 more source
Shouchella clausii, a spore‐forming Gram‐positive bacterium with a long‐standing use as probiotic, has long been considered genetically intractable. This study introduces a high‐efficiency electroporation protocol and a versatile Golden Gate‐compatible shuttle vector (pM4B522), enabling precise, scarless and iterative genome editing in both S.
Claudia Cappella +6 more
wiley +1 more source
Yeast‐Based Biotechnology for Civilian Security
Yeasts constitute robust and versatile eukaryotic platforms for biotechnological applications relevant to civilian security. Both native and genetically engineered yeast systems enable sensitive detection of chemical and biological hazards, effective removal of metals and organic pollutants, and detoxification of mycotoxins.
Justyna Ruchała +2 more
wiley +1 more source
A Novel Human Cellular System for Studying Normal Aging and for Anti‐Aging Discovery
This study introduces a human cellular aging model using placental trophoblasts (hTSC‐STBs) that mimics key aging features like senescence and genomic instability. It aligns with human tissue aging and responds to anti‐aging treatments, offering a scalable platform to screen potential therapies and bridge lab findings to clinical applications ...
Zhen Feng +14 more
wiley +1 more source
The Secretome of Human Trophoblast Stem Cells Attenuates Senescence‐Associated Traits
Human trophoblast stem cell‐derived secretome/conditioned medium (hTSC‐CM) and the extracellular vesicles (EVs) therein suppress DNA damage and NF‐κB activation in senescent fibroblasts, in turn reducing the production of senescence‐associated secretory phenotype (SASP) factors. This study highlights hTSC‐CM and EVs as potential senotherapeutic agents.
Kotb Abdelmohsen +18 more
wiley +1 more source
Hevin Promotes Aging‐Related Cardiac Dysfunction via Facilitating Cardiac Inflammation in Male Mice
Hevin released by iWAT into circulation stimulates cardiac macrophages through TLR4, inducing their polarization and CCL5 secretion, leading to worsened cardiac dysfunction and subsequent recruitment of additional inflammatory cells for pro‐inflammatory factor release.
Shi‐Yu Huang +4 more
wiley +1 more source
Unrestrained Cdc42 activity causes failure of cytotoxic function of old NK cells. This is associated with disruption of microtubular network and impaired mitochondrial ATP resulting in reduced conjugation and impaired degranulation of lytic vesicles.
Albert Kallon Koroma +15 more
wiley +1 more source
Hidrólise de oligossacarídeos de rafinose, presentes em produtos de soja, por α -galactosidases
Carina Marin Callegari
openalex +1 more source

