Results 261 to 269 of about 57,508 (269)

Periodic Therapeutic Phlebotomy Mitigates Systemic Aging Phenotypes by Promoting Bone Marrow Function

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
In D‐galactose‐induced aging model, periodic therapeutic phlebotomy exerts significant and comprehensive anti‐aging effects by inducing bone marrow microenvironment restoration, which rebalances hematopoiesis to restore peripheral blood function and ameliorate systemic aging phenotypes.
Ji‐Ru Cai   +7 more
wiley   +1 more source

Adipose‐Specific GHR Deletion Attenuates Brain Aging and Cognitive Decline in Aged Mice

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Adipose GHR deletion counteracts brain aging and cognitive decline in aged mice. This identifies adipose GH signaling as a peripheral regulator of neuroprotection and cognition. ABSTRACT Brain aging is marked by neuronal loss, synaptic deterioration, neuroinflammation, and proteinopathies, all of which contribute to cognitive decline. Although systemic
Yue Zhang   +6 more
wiley   +1 more source

The Immunogenicity of Human Senescent Cells Is Dependent on the Senescence Inducer and Cell Type

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Using multiple cell types and autologous immune cells, the authors present the first comprehensive evaluation of the immunogenicity of human senescent cells. Their findings demonstrate that, despite exhibiting a unique immunopeptidome, senescent fibroblasts are not recognized by immune cells.
Marie‐Lyn Goyer   +11 more
wiley   +1 more source

SEPARATION OF ENZYME SOLUTION OF SOUR CHERRY (PRUNUS CERASUS L.) AND IDENTIFICATION OF β-GALACTOSIDASE

Acta Horticulturae, 2005
Different sour cherry cultivars (cv. 'Erdi botermo', 'Kantorjanosi' and 'Pandy 279') were harvested than stored for 30 days at 4-6°C, 89-90% RH. The absorbance pattern of juice was different between fresh and stored fruits, especially in case of cv. 'Kantorjanosi'. No remarkable differences was found in cv. 'Erdi botermo' fresh and stored.
E. Kovács   +2 more
openaire   +1 more source

GM1 gangliosidosis and Morquio B disease: expression analysis of missense mutations affecting the catalytic site of acid β-galactosidase

Human Mutation, 2009
Alterations in GLB1, the gene coding for acid beta-D-galactosidase (beta-Gal), can result in GM1 gangliosidosis (GM1), a neurodegenerative disorder, or in Morquio B disease (MBD), a phenotype with dysostosis multiplex and normal central nervous system (CNS) function.
Hofer, Doris   +13 more
openaire   +3 more sources

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