Therapeutic Innovation from Plant-Derived Thai Herbal Extracts: α-Glucosidase Inhibitory Activity, Mechanistic Insights and Formulation Potential of the Selected Thai Rejuvenation Remedy. [PDF]
Sangkanu S +7 more
europepmc +1 more source
The Crocus sativus (saffron) aqueous extract mediated green synthesis of iron oxide nanoparticles and their in vitro and in vivo biological investigations. ABSTRACT The present study reports the green synthesis of iron oxide nanoparticles (IONPs) using the aqueous extract of Crocus sativus (saffron) as a natural reducing and stabilizing agent, followed
Abdur Rauf +10 more
wiley +1 more source
Molecular docking, DFT analysis, pharmacokinetic profiling and MD simulation of Ilex aquifolium L. flavonoids as potential α-glucosidase predicted inhibitors for diabetes. [PDF]
Alnajeebi AM.
europepmc +1 more source
We employed an 18‐month pot experiment and an integrated multi‐omics approach to elucidate the potential mechanisms underlying synthetic community (SynCom)‐mediated macadamia growth promotion. SynCom inoculation enhanced soil nitrogen cycling and potential nutrient (e.g., iron) acquisition.
Xiaofang Yao +5 more
wiley +1 more source
Synthesis of Some Novel Chalcone and 3,5-Disubstituted Pyrazoline Derivatives: Evaluation of Their α-Amylase and α-Glucosidase Inhibitory Activities In Vitro and In Silico. [PDF]
Erbay F +6 more
europepmc +1 more source
The graphical abstract represents the underlying neuroprotective potential of ICS II against Alzheimer's disease, Cerebral ischemia and Parkinson disease. ICS II downregulates ROS production, inflammation, mitochondrial dysfunction and apoptosis along with regulating their key signalling pathways.
Ashutosh Solanki +4 more
wiley +1 more source
Maltose metabolism in serum free CHO culture involves lysosomal acid α-glucosidase. [PDF]
Tan TRM +7 more
europepmc +1 more source
Intelligent design of artificial biocatalyst for biomedical diseases
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang +3 more
wiley +1 more source
Retraction Note: Dandelion flower-fabricated Ag nanoparticles versus synthetic ones with characterization and determination of photocatalytic, antioxidant, antibacterial, and α-glucosidase inhibitory activities. [PDF]
Yousefzadeh-Valendeh S +3 more
europepmc +1 more source
ABSTRACT Aspartylglucosaminuria (AGU) is a lysosomal storage disorder caused by a deficiency of aspartylglucosaminidase (AGA), a hydrolase involved in the degradation of N‐glycosylated proteins. Currently, no approved therapies are available for AGU. Development of enzyme replacement therapy (ERT) for AGU has been hampered by the complex proteolytic ...
Antje Banning +3 more
wiley +1 more source

