Results 91 to 100 of about 1,369,314 (252)

Rapidly screening of α-glucosidase inhibitors from Dioscorea opposita Thunb. peel based on rGO@Fe3O4 nanocomposites microreactor

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Present study aimed to immobilise the α-glucosidase on suitable supports to construct enzymatic microreactors and their subsequent applicability in efficient inhibitor screening from the Chinese Yam (Dioscorea opposita Thunb.) peel.
Songsong Zhang, Beibei Qiu, Jinhua Zhu, Weiping Hu, Fanyi Ma, M. Z. H. Khan, Xiuhua Liu   +6 more
doaj   +1 more source

A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation

Food Chemistry International, EarlyView.
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee, Tien‐Fen Kuo, Chun‐Yen Yang, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

α-amylase and α-glucosidase inhibitor activities of secondary metabolites from Arcytophyllum thymifolium

, 2016
Plants belonging to Arcytophyllum genus are widespread in Central and South America mainly in Costa Rica, Panama, Venezuela, Colombia, Ecuador, Peru and Bolivia [1].
Faraone, I., Vera Saltos, M. B., Milella, L., DE LEO, MARINELLA, De Tommasi, N., BRACA, ALESSANDRA, Malafronte, N.   +6 more
core   +1 more source

Phytoconstituents of Endiandra kingiana; antidiabetic effects and molecular docking studies on alpha-amylase and alpha-glucosidase

, 2023
Phytochemical investigation on the bark of E. kingiana plant afforded ten compounds, including six polyketides namely kingianin A 1, kingianin B 2, kingianin E 3, kingianin F 4, kingianin K 5 and kingianin L 6, three endiandric acids; kingianic acid A 7,
Mohamad Hafizi Abu Bakar (10528601), Muhamad Fairus Noor Hassim (17455244), Mohamad Nurul Azmi (3716179), Nurul Huda Abdul Wahab (17455247), Nurulfazlina Edayah Rasol (13133305), M. Maulidiani (2898296), Ahmad Nazif Aziz (17455241), Khalijah Awang (236138), Nurul Najihah Husna Tanazi (17455238), Nurunajah Ab Ghani (4586425)   +9 more
core   +1 more source

Nutritional, Functional, and Anti‐Hypercholesterolemic Properties of Sourdough Breads From Unripe Plantain, Tiger Nut, and Fenugreek Flours

Food Chemistry International, EarlyView.
Composite sourdough breads were developed from blends of unripe plantain, tiger nut, and fenugreek flours. Optimized formulations improved pasting stability and enhanced texture, producing softer more elastic crumbs. The enriched breads contained higher dietary fiber and bioactive compounds, and significantly reduced serum cholesterol markers ...
Mary T. Ademosun, Olufunmilayo S. Omoba, Ganiyu Oboh, Adedamola I. Akinyede, Rukayat O. Awolola   +4 more
wiley   +1 more source

Potential of Bee Pollen as a Nutraceutical And/Or Functional Ingredient for Metabolic Syndrome Management: In Vitro Antioxidant, Anti‐Inflammatory, and Digestive Enzyme Inhibitory Activities

Food Chemistry International, EarlyView.
Bee pollen samples from China and Spain exhibited in vitro antioxidant, anti‐inflammatory, and digestive enzyme inhibitory activities due to their composition, suggesting their potential as a nutraceutical or functional ingredient to help counteract oxidative stress, chronic inflammation, and metabolic disorders.
Adriana Maite Fernández‐Fernández, Victoria Olt, Jessica Báez, Marcelo Miraballes, Melissa Romero, Cecilia Dauber, Ignacio Vieitez, Estela Santos, Adriana Gámbaro, Alejandra Medrano   +9 more
wiley   +1 more source

Supplementary material - Supplemental material for Carbazomarin: A New Potential of α-Glucosidase Inhibitor From Clausena excavata Roots

, 2020
Supplemental material, Supplementary material, for Carbazomarin: A New Potential of α-Glucosidase Inhibitor From Clausena excavata Roots by Nanik S. Aminah, Tin M. Thant, Alfinda N. Kristanti, Rico Ramadhan, Hnin T.
Hnin T. Aung (8598846), Yoshiaki Takaya (1776925), Alfinda N. Kristanti (8598843), Nanik S. Aminah (8598837), Rico Ramadhan (4441459), Tin M. Thant (8598840)   +5 more
core   +1 more source

“Nature's Polymer Reimagined: Conventional and Green Routes to Pectin, Its Bioactive Promise and Industrial Applications”

Food Chemistry International, EarlyView.
Pectin, a versatile natural polymer, is extracted through conventional and emerging green extraction methods, offering multifunctional bioactive properties useful in food, pharmaceutical, and environmental applications. ABSTRACT Pectin, a molecular tapestry woven from diverse polysaccharides, holds a pivotal role across food, pharmaceutical, and ...
Afra Anika Rafique, Aunwesha Sahani, Md Morsaline Billah, Kazi Mohammed Didarul Islam   +3 more
wiley   +1 more source

Glucosidase-Catalyzed Hydrolysis of α-d-Glucopyranosyl Pyridinium Salts:  Kinetic Evidence for Nucleophilic Involvement at the Glucosidation Transition State

, 2016
Kinetic isotope effects (KIEs) on the yeast α-glucosidase-catalyzed hydrolysis of two α-d-glucopyranosyl pyridinium salts were measured at 25 °C and pH = 6.8. The measured KIEs on kcat for the 2H-2, 13C-1, and 15N-1‘ labeled substrates α-d-glucopyranosyl
Xicai Huang (2676652), Kelly S. E. Tanaka (2409535), Andrew J. Bennet (1755919)   +2 more
core   +1 more source

Effect of Pretreatment Methods on the Proximate Composition, Antinutritional Factors, Antioxidants Properties, and In Vitro Antidiabetic Activities of Hypsizygus ulmarius

Food Chemistry International, EarlyView.
The effect of pretreatment methods on the proximate content, antinutrient factors, antioxidant, and in vitro antidiabetic activities of elm oyster mushroom was studied. It was observed and statistically concluded that soaking in 0.5% salt solution for 5 min had the least deteriorating effect on the antioxidant and in vitro antidiabetic activities ...
Oluwadamilola Ogunsade, Saka Olasunkanmi Gbadamosi, Tunde Afolabi Morakinyo, Adedayo Olubunmi Adeboye, Akinsola Albert Famuwagun   +4 more
wiley   +1 more source