Results 111 to 120 of about 1,369,314 (252)

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

Design, synthesis, biological evaluation, and molecular modeling studies of pyrazole-benzofuran hybrids as new α-glucosidase inhibitor. [PDF]

Sci Rep, 2021
Azimi F, Azizian H, Najafi M, Khodarahmi G, Saghaei L, Hassanzadeh M, Ghasemi JB, Faramarzi MA, Larijani B, Hassanzadeh F, Mahdavi M.   +10 more
europepmc   +1 more source

Bromelain as the enzyme of the future: A global bibliometric mapping of its applications and emerging trends

Journal of the Science of Food and Agriculture, EarlyView.
Abstract INTRODUCTION Bromelain, a complex mixture of proteolytic enzymes primarily extracted from plants of the Bromeliaceae family, has gained prominence because of its broad industrial applicability, particularly in the food, pharmaceutical and cosmetic sectors.
Genésio José da Silva Neto, Tonny Cley Campos Leite, Mônica Tejo Cavalcanti, Geany Targino Sousa Pedrosa, Rerisson do Nascimento Alves, Amanda Reges de Sena, Mônica Correia Gonçalves   +6 more
wiley   +1 more source

Phytochemical constituent, α-amylase and α-glucosidase inhibitory activities of Black Soybean (Glycine soja (L.) Merr.) ethanol extract

Pharmaciana
Diabetes is characterized as a hyperglycemic condition impacted by β-cell dysfunction and insulin deficiency. Black soybean (Glycine soja (L.) Merr.) is widely known as an origin of nutritious food that has shown activities in preventing cardiovascular ...
Afifah Bambang Sutjiatmo, Suci Narvikasari, Ananda Khairunisa Solihat, Wahyu Widowati, Hanna Sari Widya Kusuma, Fadhilah Haifa Zahiroh   +5 more
doaj   +1 more source

Inhibitory effect of hesperetin on α-glucosidase: Molecular dynamics simulation integrating inhibition kinetics

, 2017
The α-glucosidase inhibitor is of interest to researchers due to its association with type-2 diabetes treatment. Hesperetin is a flavonoid with natural antioxidant properties.
X Y Qin, Yan Gong, Xiu-Yuan Qin, Yuan-Yuan Zhai, Yong-Doo Park, Y Y Zhai, H Hao, Jinhyuk Lee, Y Gong, Hao Hao, Y D Park   +10 more
core   +1 more source

Bio‐guided fractionation of (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid from Abelmoschus sagittifolius root as a potent α‐glucosidase inhibitor: An integrated in vitro and in silico study

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Abelmoschus sagittifolius stands out as a valuable medicinal source for developing functional food targeting type 2 diabetes. This study investigated the α‐glucosidase inhibitory potential of an active fraction obtained from A. sagittifolius roots (ASR), enriched in (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid (OA), using both enzyme ...
Nguyen Phuong Mai, Nguyen Van Quan, Nguyen Dang Duc, Tran Dang Xuan   +3 more
wiley   +1 more source

Chemical synthesis, inhibitory activity and molecular mechanism of 1-deoxynojirimycin-chrysin as a potent α-glucosidase inhibitor. [PDF]

RSC Adv, 2021
Zhang R, Zhang Y, Huang G, Xin X, Tang L, Li H, Lee KS, Jin BR, Gui Z.   +8 more
europepmc   +1 more source

α-GLUCOSIDASE INHIBITOR AND ANTIOXIDANT ACTIVITY ASSAYS OF GUAVA LEAF, CASHEW LEAF AND THE COMBINATIONS AS ANTIDIABETIC AGENT

International Journal of Research in Ayurveda & Pharmacy, 2017
Asep Sukohar, Samsu Udayana N, Diana Mayasari, Arli Suryawinata   +3 more
openaire   +1 more source

Characterising the selectivity of ER α-glucosidase inhibitors

, 2019
The endoplasmic reticulum (ER) contains both α-glucosidases and α-mannosidases which process the N-linked oligosaccharides of newly synthesised glycoproteins and thereby facilitate polypeptide folding and glycoprotein quality control.
High, Stephen; id_orcid, Roebuck, Quentin P, O'keefe, Sarah, Hirono, Shuichi, Nakagome, Izumi, Nash, Robert, Kato, Atsushi   +6 more
core   +1 more source