Results 131 to 140 of about 1,369,314 (252)

Optimizing the Preparation Process and Antioxidant Activity of α-Glucosidase Inhibitory Peptide from Cinnamomum camphora Seed Kernel

open access: yesShipin gongye ke-ji
To achieve high-value development and use of the abundant Cinnamomum camphora seed resources in China and screen the α-glucosidase inhibitor peptides derived from Cinnamomum camphora seed kernel (CCSK), the aim of this study was to produce α-glucosidase ...
Weiyun WANG   +5 more
doaj   +1 more source

TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum

open access: yesInsect Science, EarlyView.
RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li   +8 more
wiley   +1 more source

Exploring the inhibitory effect and mechanism of 3,4,5-trihydroxybiphenyl on α-glucosidase: an integrated experimental and computational approach

open access: yesFrontiers in Pharmacology
3,4,5-Trihydroxybiphenyl (THB) is a naturally occurring compound derived from Sorbus pohuashanensis, primarily reported for its antifungal activity. However, its potential to inhibit α-glucosidase remains unclear.
Ruofan Guo   +15 more
doaj   +1 more source

Timing and duration of glucagon‐like peptide‐1 receptor agonist use and risk of nonarteritic anterior ischaemic optic neuropathy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To investigate the association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and nonarteritic anterior ischaemic optic neuropathy (NAION) in type 2 diabetes, examining treatment recency and cumulative duration. Methods This nationwide registry‐based nested case–control study utilizedz Danish health registries (1996 ...
Siar Niazi   +9 more
wiley   +1 more source

Successfully Treated Pneumatosis Cystoides Intestinalis with Pneumoperitoneum Onset in a Patient Administered α-glucosidase Inhibitor

open access: yes
An 80-year-old woman, who had been administered α-glucosidase inhibitor for diabetes, was brought to the hospital with the sensation of abdominal fullness and pain.
Tanabe, Shunsuke   +8 more
core  

Bowel Obstruction/Ileus Associated With the Use of Glucagon‐Like Peptide‐1 Receptor Agonists: A Nationwide Database Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and the development of bowel obstruction/ileus remains unclear, and evidence for specific bowel obstruction/ileus subtypes remains limited. We examined the association between GLP‐1RA use and the incidence of bowel obstruction/ileus subtypes across different ...
Yuichiro Matsuo   +3 more
wiley   +1 more source

Studies on α-glucosidase inhibitors and antibacterial materials produced by Paenibacillus sp. TKU037

open access: yes, 2017
碩士菌株TKU037係篩選自淡水土壤,液態發酵NB (Nutrient Broth) 能生產α-葡萄糖苷酶抑制劑和抗菌物質,經鑑定係屬類芽胞桿菌(Paenibacillus sp.)之一株細菌。本研究探討Paenibacillus sp. TKU037生產α-葡萄糖苷酶抑制劑之較適條件,以及所生產α-葡萄糖苷酶抑制劑之pH值與熱安定性,並且分離出具α-葡萄糖苷酶抑制活性之一化合物1-methylhydantoin。Bacterial strain TKU037 produced α ...
施柏豪;Shih, Po-Hao
core  

Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response

open access: yesThe FEBS Journal, EarlyView.
Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril   +2 more
wiley   +1 more source

Elucidation of Potent Mammalian Enzymes Inhibitors Targeting Anti-Diabetes Drug from Castanea mollissima Blume, 1851: An Edible Herbal Collected in Vietnam via Experimental and Computation Approaching

open access: yes
This study aimed to explore the extracts of Castanea mollissima Blume, 1851 as rich sources of enzyme inhibitors targeting type 2 diabetic (T2D) drugs.
Wang, San-lang
core   +1 more source

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