Study on α-Glycosidase Inhibitor from Magnolia offcinalis Rehder et Wils
本论文由三章组成。 第一章是关于厚朴中具有α-葡萄糖苷酶抑制活性成分的研究。凹叶厚朴的乙醇提取物显示了较强的α-葡萄糖苷酶抑制活性。为了确定其活性成分,在活性测试的指导下,通过溶剂萃取、树脂吸附和反复硅胶柱层析等分离方法从凹叶厚朴乙醇提取物中分离得到6 个生物碱,并用质谱和核磁共振等波谱方法分别鉴定为:木兰箭毒碱,木兰花碱,鹅掌楸碱,蕃荔枝碱,罗默碱和Lysicamine。应用小肠α-葡萄糖苷酶模型测定了它们对α-葡萄糖苷酶的抑制作用。其中,番荔枝碱和木兰箭毒碱对α-葡萄糖苷酶相对抑制活性最好 ...
瞿庆喜
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Background: The inherent glycosidase inhibitory activity and potentially therapeutic value of the polyhydroxylated pyrrolizidine alkaloids containing a hydroxymethyl substituent at the C-3 position have been well documented.
Anthony Carroll (20116878) +1 more
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Triterpenoid Saponins and Flavonoid Glycosides from the Flower of Camellia flavida and Their Cytotoxic and α-Glycosidase Inhibitory Activities. [PDF]
Ma S, Wu Y, Min H, Ge L, Yang K.
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Effect of α-glycosidase inhibitors from endophytic fungus Alternaria destruens on survival and development of insect pest Spodoptera litura Fab. and fungal phytopathogens. [PDF]
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Κριτική - Έτος Α' τευχ. 1-12 (15 Ιουνίου 1923 - 30 Μαΐου 1924)
Στο Έτος Α’ περιλαμβάνονται 12 ...
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Innovation of 6-sulfonamide-2H-chromene derivatives as antidiabetic agents targeting α-amylase, α-glycosidase, and PPAR-γ inhibitors with in silico molecular docking simulation. [PDF]
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Unnatural C6-Substituted d-Galactosides as Attenuated Substrates of Glycosyl Hydrolases. [PDF]
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Synthesis and glycosidase inhibiton of two types of <i>N</i>-alkylated 1-deoxynojirimycin derivatives. [PDF]
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