Results 91 to 100 of about 741,770 (157)

Image_3_Enhanced Expression of Secreted α-Klotho in the Hippocampus Alters Nesting Behavior and Memory Formation in Mice.TIFF

, 2019
The klotho gene family consists of α-, β-, and γ-Klotho, which encode type I single-pass transmembrane proteins with large extracellular domains. α-Klotho exists as a full-length membrane-bound and as a soluble form after cleavage of the extracellular ...
Thomas Behnisch (355864), Ying Chen (9697), Fang Huang (154302), Dongqing Jing (6533705), Ziyang Liu (242055), Dongxue Li (835305)   +5 more
core   +1 more source

Association between plasma trans fatty acids and serum α-klotho levels in adults in the United States of America: an analysis of the NHANES 2009–2010 datasets

Lipids in Health and Disease
Background This study aimed to explore the potential associations between trans fatty acid (TFA) and α-klotho levels. Methods Datasets from the 2009–2010 National Health and Nutrition Examination Survey (NHANES) were analysed for this study ...
Yali Liang, Yu Zhu, Min Zhang, Yuxiao Zhang, Shanjiamei Jiang, Xinzhi Wang, Fan Yu, Jie Ma, Yue’e Huang   +8 more
doaj   +1 more source

Image_2_Enhanced Expression of Secreted α-Klotho in the Hippocampus Alters Nesting Behavior and Memory Formation in Mice.TIFF

, 2019
The klotho gene family consists of α-, β-, and γ-Klotho, which encode type I single-pass transmembrane proteins with large extracellular domains. α-Klotho exists as a full-length membrane-bound and as a soluble form after cleavage of the extracellular ...
Thomas Behnisch (355864), Ying Chen (9697), Fang Huang (154302), Dongqing Jing (6533705), Ziyang Liu (242055), Dongxue Li (835305)   +5 more
core   +1 more source

Development of an α‑Klotho Recognizing High-Affinity Peptide Probe from In-Solution Enrichment

The kidney, parathyroid gland, and choroid plexus express the aging-related transmembrane protein α-Klotho, a coreceptor of the fibroblast growth factor 23 (FGF23) receptor complex.
Bradley L. Pentelute (1247046), Peiyuan Zhang (6940700), Silvino Sousa (5338634), Magdalena Preciado López (18341275), John C. K. Wang (17194237), Xiyun Ye (530088), Andrei Loas (1233750), Dan L. Eaton (2686705), Corey L. Smith (17609671)   +8 more
core   +1 more source

The relationship between serum alpha-klotho levels and urinary incontinence in middle-aged and older females: insights from NHANES

Scientific Reports
Urinary incontinence (UI) in females is a prevailing condition that affects individuals across various age groups and is not limited to older females. The presence of serum alpha-Klotho (α-klotho) serves as a reliable biomarker to indicate the effects of
Xiaoyan Tang, Yanhua Song, Hao Liang, Wenjin He, Zili Chen, Li Yang, Cheng Yang, Rui Du   +7 more
doaj   +1 more source

Association between serum alpha Klotho levels and the likelihood of abdominal aortic calcification

Scientific Reports
As an anti-aging protein, alpha Klotho (α-Klotho) plays an important role in cardiovascular disease. However, the correlation between α-Klotho and abdominal aortic calcification (AAC) is unclear.
Dan Liang, Chang Liu, Mei Yang
doaj   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

The prognostic value of serum α-klotho in age-related diseases among the US population: A prospective population-based cohort study

Preventive Medicine Reports
Objective: α-Klotho is a potential biological marker of aging with satisfactory clinical applicability. However, its prognostic significance in age-related diseases has largely been undermined.
Zhiwen Yang, Yusheng Ma, Yanbing Wang, Ming Jin, Jianping Bin, Zhiyong Chen, Zhonghua Teng   +6 more
doaj   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

α-Klotho regulates age-associated vascular mineralization and lifespan in zebrafish

, 2019
α-Klotho is an anti-aging hormone regulating mineral homeostasis together with Fibroblast Growth Factor-23 (FGF23) in mammals. Cellular and molecular mechanisms through which these signals regulate age-related conditions, such as vascular mineralization ...
Wetzel, Kristie, Fishman, Mark, Tang, Wenlong, Sanchez, Ellen, Hubaud, Alexis, Wang, Guangliang, Molind, Gregory, Singh, Ajeet, Fang, Jian, Glass, David, Cadena, Samuel, Coble, Matthew, Shanmukhappa, Shiva, Fawcett, Caroline, Sosa, Maria, Tsai, Ting, Capodieci, Paola   +16 more
core   +1 more source