The Role of α-Linolenic Acid and Its Oxylipins in Human Cardiovascular Diseases. [PDF]
Int J Mol Sci, 2023 α-linolenic acid (ALA) is an essential C-18 n-3 polyunsaturated fatty acid (PUFA), which can be elongated to longer n-3 PUFAs, such as eicosapentaenoic acid (EPA).
Cambiaggi L +3 more
europepmc +2 more sources
The Effects of a Low Linoleic Acid/α-Linolenic Acid Ratio on Lipid Metabolism and Endogenous Fatty Acid Distribution in Obese Mice. [PDF]
Int J Mol Sci, 2023 A reduced risk of obesity and metabolic syndrome has been observed in individuals with a low intake ratio of linoleic acid/α-linolenic acid (LA/ALA). However, the influence of a low ratio of LA/ALA intake on lipid metabolism and endogenous fatty acid ...
Wang Q, Wang X.
europepmc +2 more sources
Impact of α-Linolenic Acid, the Vegetable ω-3 Fatty Acid, on Cardiovascular Disease and Cognition. [PDF]
Adv Nutr, 2022 Given the evidence of the health benefits of plant-based diets and long-chain n–3 (ω-3) fatty acids, there is keen interest in better understanding the role of α-linolenic acid (ALA), a plant-derived n–3 fatty acid, on cardiometabolic diseases and ...
Sala-Vila A +3 more
europepmc +2 more sources
The Antitumor Effects of α-Linolenic Acid. [PDF]
J Pers Medα-linolenic acid (ALA), which is a member of the n-3 polyunsaturated fatty acid (n-3 PUFA) family, has often been ignored due to a lack of information.
Yan H +7 more
europepmc +2 more sources
Correlation between gut bacteria Phascolarctobacterium and exogenous metabolite α-linolenic acid in T2DM: a case-control study. [PDF]
Ann Transl Med, 2022 Background The relationship between gut microbiota and metabolites play an important role in the occurrence and development of type 2 diabetes mellitus (T2DM).
Li W, Li L, Yang F, Hu Q, Xiong D.
europepmc +2 more sources
α-Linolenic Acid Suppresses Proliferation and Invasion in Osteosarcoma Cells via Inhibiting Fatty Acid Synthase. [PDF]
Molecules, 2022 Fatty acid synthase (FASN) is highly expressed in multiple types of human cancers and is recognized as one of the targets for treating cancer metastasis.
Fan H, Huang W, Guo Y, Ma X, Yang J.
europepmc +2 more sources
Effects of Dietary α-Linolenic Acid Treatment and the Efficiency of Its Conversion to Eicosapentaenoic and Docosahexaenoic Acids in Obesity and Related Diseases. [PDF]
Molecules, 2022 The essential fatty acid alpha-linolenic acid (ALA) is present in high amounts in oils such as flaxseed, soy, hemp, rapeseed, chia, and perilla, while stearidonic acid is abundant in echium oil.
Takic M +3 more
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α- Linolenic acid modulates phagocytosis and endosomal pathways of extracellular Tau in microglia. [PDF]
Cell Adh Migr, 2021 Microglia, the resident immune cells, were found to be activated to inflammatory phenotype in Alzheimer’s disease (AD). The extracellular burden of amyloid-β plaques and Tau seed fabricate the activation of microglia.
Desale SE, Chinnathambi S.
europepmc +2 more sources
Frontiers in Plant Science, 2021 Climate changes especially chilling stress affects cucurbit crops during winter seasonal production. Grafting to pumpkin rootstocks is widely used to improve the vigor of cucurbits, especially cucumber (Cucumis sativus L.) plants, in the face of chilling
Wen-quan Liu +12 more
semanticscholar +1 more source
Frontiers in Endocrinology, 2020 Polycystic ovary syndrome (PCOS) represents a common endocrine—metabolic disorder disease with chronic low-grade inflammation and alteration of intestinal flora.
Ting Wang +10 more
semanticscholar +1 more source