Results 31 to 40 of about 2,390 (158)

Sulfur-containing benzofurans and α-pyrones from the mangrove-derived fungus Talaromyces sp. WHUF0341

Frontiers in Marine Science, 2022
Two new sulfur-containing benzofurans, talarobenzofurans A and B (1 and 2), one new benzofuran talarobenzofuran C (3) and two new α-pyrones talaropyrones A and B (5 and 6), along with five known compounds eurothiocin A (4), nodulisporipyrone A (7 ...
Ruohan Zhang, Ruohan Zhang, Jinxin Zhang, Jinxin Zhang, Ruiyun Huo, Ruiyun Huo, Yaxin Xue, Kui Hong, Ling Liu, Ling Liu   +9 more
doaj   +1 more source

Assignment of Absolute Configurations of Two Promising Anti-Helicobacter pylori Agents from the Marine Sponge-Derived Fungus Aspergillus niger L14

Molecules, 2021
A chemical investigation into endozoic fungus Aspergillus niger L14 derived from the marine sponge of Reniera japonica collected off Xinghai Bay (China) resulted in the isolation of two dimeric naphtho-γ-pyrones, fonsecinone A (1) and isoaurasperone A (2)
Jia Liu, Ronglu Yu, Jia Jia, Wen Gu, Huawei Zhang   +4 more
doaj   +1 more source

Bioactive α-Pyrone Derivatives from the Endophytic Fungus Diaporthe sp. CB10100 as Inducible Nitric Oxide Synthase Inhibitors

Frontiers in Chemistry, 2021
Inducible nitric oxide synthase (iNOS) produces NO from l-arginine and plays critical roles in inflammation and immune activation. Selective and potent iNOS inhibitors may be potentially used in many indications, such as rheumatoid arthritis, pain, and ...
Hong Pu, Hong Pu, Hong Pu, Jianxin Liu, Yeji Wang, Yuhui Peng, Wanying Zheng, Yang Tang, Boping Hui, Chunmei Nie, Xueshuang Huang, Yanwen Duan, Yanwen Duan, Yanwen Duan, Yong Huang, Yong Huang   +15 more
doaj   +1 more source

Combinatory Exposure to Urolithin A, Alternariol, and Deoxynivalenol Affects Colon Cancer Metabolism and Epithelial Barrier Integrity in vitro

Frontiers in Nutrition, 2022
The human gastrointestinal tract is an important site of nutrient absorption and a crucial barrier against xenobiotics. It regularly faces “chemical cocktails” composed of food constituents, their human and microbial metabolites, and foodborne ...
Julia Groestlinger, Carina Seidl, Elisabeth Varga, Giorgia Del Favero, Giorgia Del Favero, Doris Marko   +5 more
doaj   +1 more source

Convergent Total Synthesis of 16β‐Hydroxylpseudobufarenogin

Angewandte Chemie, Volume 138, Issue 23, 1 June 2026.
We present a novel convergent strategy that integrates Pd/Ag‐promoted Suzuki–Miyaura coupling with Ir‐catalyzed radical‐relay cyclization, enabling the first total synthesis of 16β‐hydroxylpseudobufarenogin. This approach is broadly applicable to the total synthesis of various oxygenated bufadienolides by simply modifying the fragment structures ...
Wataru Shigematsu, Yo Matsumoto, Koichi Hagiwara, Masayuki Inoue   +3 more
wiley   +2 more sources

Integration of Antimicrobials and Delivery Systems: Synergistic Antibiofilm Activity with Biodegradable Nanoemulsions Incorporating Pseudopyronine Analogs

Antibiotics, 2023
Multi-drug-resistant (MDR) bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), pose a significant challenge in healthcare settings.
Jungmi Park, Neel Mahida, Gabrielle Ho, Elizabeth Pena, Jessa Marie V. Makabenta, Stanley Aneke, Mingdi Jiang, Leah M. Bouthillette, Stephanie E. Holz, Muhammad Aamir Hassan, Amanda L. Wolfe, Vincent M. Rotello   +11 more
doaj   +1 more source

Two New Pyrone Derivatives from the Plant Endophytic Fungus sp

Natural Product Communications, 2014
Two new α-pyrones, Exserolide G–H (1–2) , together with one known metabolite, stemphypyrone (3) , were isolated from the solid-substrate fermentation cultures of the plant endophytic fungus Exserohilum sp.
Ruxin Li, Shubin Niu, Liangdong Guo, Yang Zhang   +3 more
doaj   +1 more source

Secondary Metabolites, Biological Activities, and Industrial and Biotechnological Importance of Aspergillus sydowii

Marine Drugs, 2023
Marine-derived fungi are renowned as a source of astonishingly significant and synthetically appealing metabolites that are proven as new lead chemicals for chemical, pharmaceutical, and agricultural fields.
Sabrin R. M. Ibrahim, Shaimaa G. A. Mohamed, Baiaan H. Alsaadi, Maryam M. Althubyani, Zainab I. Awari, Hazem G. A. Hussein, Abrar A. Aljohani, Jumanah Faisal Albasri, Salha Atiah Faraj, Gamal A. Mohamed   +9 more
doaj   +1 more source

Pyran Rings Containing Polyketides from Penicillium raistrickii

Marine Drugs, 2016
Five new pyran rings containing polyketides, penicipyrans A–E (1–5), together with the known pestapyrone A (6), were isolated from the saline soil-derived Penicillium raistrickii. Their structures were determined by interpretation of NMR and HRESIMS data.
Li-Ying Ma, De-Sheng Liu, De-Guo Li, Yu-Ling Huang, Hui-Hui Kang, Chun-Hua Wang, Wei-Zhong Liu   +6 more
doaj   +1 more source

Mesityl‐Substituted Azuleno[1′,2′:4,5]pyrrolo[2,3‐b]quinoxalines: Synthesis, Functionalization, Photophysical, and Electrochemical Properties

European Journal of Organic Chemistry, EarlyView.
Azuleno[1′,2′:4,5]pyrrolo[2,3‐b]quinoxaline with a mesityl group as a solubilizing group was synthesized. By synthesizing derivatives in which various functional groups were introduced into two electronically distinct sites, the pyrrole nitrogen atom and the azulene five‐membered ring, we were able to reveal that the photophysical and electrochemical ...
Ryuta Sekiguchi, Hiroki Mizuno, Ikumi Uchiyama, Souta Yuruka, Atsuya Shimizu, Taku Shoji, Shunji Ito   +6 more
wiley   +1 more source